Recommended on Univadis

  • Clinical Essentials from Br J Haematol
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First-line DLBCL: BR in elderly, frail patients delivers high response and low survival

Many patients had poor ECOG status and baseline comorbidities.

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  • Clinical Essentials from Urology
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RCC linked to greater post-op drop in renal function than urothelial carcinoma

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  • Clinical Essentials from PLoS One
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MCRC: how do elderly patients respond to treatment?

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  • Clinical Essentials from Lancet Glob Health
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War on congenital syphilis progressing, but not yet won

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  • Clinical Essentials from J Clin Oncol
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ASCO issues new guidelines for managing chronic pain in cancer survivors

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  • Conference Essentials
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Top stories reported by our editors from the 2016 International AIDS Conference

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  • Clinical Essentials from Medicine (Baltimore)
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Study nixes link between antidepressants and endometrial cancer

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  • Clinical Essentials from MMWR Morb Mortal Wkly Rep
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MMWR: HCV vertical transmission on the rise

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  • Clinical Essentials from MMWR Morb Mortal Wkly Rep.
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Zika: CDC updates guidelines for preventing sexual transmission

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Professional Essentials

  • Patients Will Be Asking
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I think my distant friend is suffering from a mental illness—how can I help them?

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  • Patients Will Be Asking
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Do I really need this skin check?

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  • US Professional News
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Rates of uninsured, unpaid medical bills down in Medicaid expansion states

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  • US Professional News
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Large corporations begin offering employees mental health benefits via smartphone

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  • US Professional News
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Psychiatrists, psychotherapists prefer working with those patients who can pay

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  • US Professional News
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Primary care physicians may experience an economic boon under risk-based payment models

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New on Univadis

  • Univadis
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HPV vaccine: low uptake in the postpartum period

Frequent encounters with the health care system render the postpartum period an ideal time for HPV vaccination.

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  • Clinical Essentials from BMJ
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Thyroid cancer: imaging improves treatment for recurrence, but not always survival

Only radioiodine scans are associated with improved disease-specific survival.

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  • Clinical Essentials from JAMA
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Birth trends: late preterm, early term birth rates in 5 high-income countries

Declining rates in United States may be due to efforts to delay elective delivery until after 39 wk.

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  • Clinical Essentials from Hepatol Int
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HCV-1b: 12-wk dual-DAA approach 100% effective in difficult-to-treat patients

Small real-world study shows 100% efficacy in treatment-experienced patients with and without cirrhosis.

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  • Clinical Essentials from Pediatr Blood Cancer
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Childhood ALL: what’s the optimal hematological target for adjusting 6MP/MTX maintenance?

Results from a Nordic study of 532 children.

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  • Clinical Essentials from Oncotarget
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Gastric cancer: patterns of metastases differ depending on histological type

Epidemiology of metastatic gastric cancer remains largely unknown.

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  • Clinical Essentials from Urol Oncol
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Node-positive prostate cancer: multimodal adjuvant therapy yields 33% decrease in mortality

Adjuvant therapy is highly controversial in this setting .

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  • Clinical Essentials from Curr Med Res Opin
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Cystic fibrosis: powder tobramycin efficacy, safety confirmed at 1 y

The formulation is more time-effective than inhalation solution, potentially improving adherence.

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  • Clinical Essentials from PLoS One
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Dementia risk linked to hearing impairment

Preserving hearing, including hearing aid use when indicated, may preserve social interaction and reduce dementia burden.

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  • Clinical Essentials from PLoS One
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Cognitive impairment linked to elevated BP in middle age, but less so in later life

Specific BP management strategies for various age groups may help preserve cognitive function.

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  • Clinical Essentials from PLoS Med
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Lifestyle programs modeled after the Diabetes Prevention Program yield multiple benefits

Programs that differ from the original DPP by setting or provider type still produce favorable changes.

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  • Clinical Essentials from PLoS Med
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Type 2 diabetes: is there a role for supported telemonitoring in primary care?

Traditional approaches are often ineffective.

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  • Clinical Essentials from Am J Respir Crit Care Med
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Cystic fibrosis: 40% of very young children show abnormal glucose tolerance

Abnormal glucose tolerance is linked to decreased lung function in CF.

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  • Clinical Essentials from Lancet Respir Med
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Severe emphysema: segmental vapor ablation shows benefit at 1 y

Targeted lung reduction reduces risk for pneumothorax, and is unaffected by fissure integrity or collateral ventilation.

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