Recommended on Univadis

  • Clinical Essentials from Prostate Cancer Prostatic Dis
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Post-docetaxel mCRPC: no survival benefit for prednisone

Prednisone was also linked to a 48% increased risk for grade 3 or higher toxicities.

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  • Clinical Essentials from Ann Oncol
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ESMO issues guidelines for metastatic NSCLC

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  • Monthly Essentials
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Lipids and CAD: Monthly Essentials September 2016

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  • Clinical Essentials from FDA press release
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FDA approves first automated insulin delivery device for type 1 diabetes

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  • Clinical Essentials from J Neurol Sci
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ALS with frontotemporal syndrome reduces survival benefit of noninvasive ventilation

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  • Clinical Essentials from JAMA Psychiatry
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Psychosis risk, cannabis use dose-dependent

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  • Clinical Essentials from Lancet Haematol
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Childhood ALL: acute leukoencephalopathy tied to later neurobehavioral issues

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  • Clinical Essentials from J Manag Care Spec Pharm
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Most RA drug coverage more restrictive than FDA label indications

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  • Clinical Essentials from J Clin Endocrinol Metab
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New practice guidelines on insulin pumps and continuous glucose monitoring

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Professional Essentials

  • Patients Will Be Asking

Is birth control going to make me depressed?

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  • Patients Will Be Asking

How can the Americas be "measles-free?"

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  • US Professional News

Digital technologies offer promising solutions to the problem of medication adherence

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  • US Professional News

Use of digital health tech in clinical trials on the rise, survey results show

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  • US Professional News

New electronic pill dispenser enables cellular monitoring of patient medication adherence

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  • US Professional News

Many physicians choose to attend patient funerals, but practice remains controversial

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New on Univadis

Predicting response to anti-HER2 therapy using RNA sequencing
  • JAMA Oncology
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Predicting response to anti-HER2 therapy using RNA sequencing

The study examines association between gene expression–based biomarkers and response to anti-HER2 therapy

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Spindle cell tumors of the salivary gland: Four cases | ESP
  • Conference Essentials
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Spindle cell tumors of the salivary gland: Four cases | ESP

The cytology of spindle cells lesions encompasses a wide variety of lesions, with potential pitfalls.

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Insulin resistance does not reduce effectiveness of DAA therapy and improves after treatment | EASL Special Conference on HCV
  • Conference Essentials
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Insulin resistance does not reduce effectiveness of DAA therapy and improves after treatment | EASL Special Conference on HCV

Insulin resistant HCV patients treated with DAA therapy achieve SVR at rates comparable to those without insulin resistance.

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Direct-acting antiviral therapy demonstrates excellent effectiveness in real-world setting | EASL Special Conference on HCV
  • Conference Essentials
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Direct-acting antiviral therapy demonstrates excellent effectiveness in real-world setting | EASL Special Conference on HCV

A meta-analysis of real-world data indicates that DAA regimens consisting of OBV/PTV/r ± DSV ± RBV are highly effective for HCV patients with genotypes 1 or 4.

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SOX2 loss predicts adverse survival of esophageal adenocarcinoma patients | ESP
  • Conference Essentials
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SOX2 loss predicts adverse survival of esophageal adenocarcinoma patients | ESP

The prognosis of EAC remains poor but is highly variable.

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  • Clinical Essentials from Ann Hematol
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Newly diagnosed FL: watch and wait remains worthwhile in the rituximab era

No meaningful differences in outcomes compared with immediately treated patients.

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  • Clinical Essentials from Ann Intern Med
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CRC: is colonoscopy screening beneficial after age 70?

US population-based data show a modest benefit that decreases with age.

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  • Clinical Essentials from BMC Pregnancy Childbirth
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Decreased fetal movement: what drives evaluation?

Better counseling may improve prompt evaluation of decreased fetal movement.

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  • Clinical Essentials from Clin Radiol
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CTA imaging technique reduces radiation by more than half

“Double-low” method reduces radiation and iodine without sacrificing image quality.

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  • Clinical Essentials from Braz J Otorhinolaryngol
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Osteoporosis linked to hearing loss

Meta-analysis shows association between hearing and BMD.

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  • Clinical Essentials from PLoS Negl Trop Dis
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Dengue virus: prognostic biomarkers identified

Biomarkers help discriminate patients at high risk for DENV shock, organ failure.

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  • Clinical Essentials from Ann Behav Med
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Smoking cessation: address depression in patients with cancer

Psychological treatments may be useful adjuncts for depressed patients in tobacco cessation programs.

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  • Clinical Essentials from AIDS
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Review: no association between HIV and gestational diabetes, minor bump for first-gen PIs

25% of people living with HIV in the United States are women.

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  • Clinical Essentials from J Clin Pharm Ther
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Hypertension: safety, efficacy of fixed-dose combo of nifedipine GI therapeutic system and candesartan cilexetil

Open-label study suggests tolerability and sustained, steep BP decreases.

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