Recommended on Univadis

  • Clinical Essentials from MMWR Morb Mortal Wkly Rep
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MMWR: HCV vertical transmission on the rise

Skyrocketing rates in Kentucky may be linked to a high prevalence of IV drug abuse.

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  • Univadis
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Meningococcal vaccine: lower than expected immunogenicity against outbreak antigens

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  • Clinical Essentials from Blood
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R/R HL: single-agent brentuximab vedotin delivers impressive sustained remission

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  • Clinical Essentials from Efficacy and Mechanism Evaluation
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Cystic fibrosis: novel nonviral gene therapy improves lung function

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  • Clinical Essentials from Eur J Surg Oncol
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Electrochemotherapy: a promising strategy for skin cancer, superficial metastases

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  • Clinical Essentials from Resp Med
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Can exposure to household bleach cause asthma?

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  • Clinical Essentials from BJU Int
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Prostate cancer: expanded primary care role is cost-effective in low to moderate-risk disease

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  • Clinical Essentials from N Engl J Med
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Is physiologic definition of COPD adequate? Expert comment

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  • Clinical Essentials from Neurology
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Multiple sclerosis: improving the accuracy of MRI diagnosis in clinically isolated syndrome

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Professional Essentials

  • Patients Will Be Asking
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What do the new warnings on Zika mean for me?

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  • Patients Will Be Asking
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Should I use a neti pot for my sinusitis?

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  • US Professional News
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ONC: New health policy needed to safeguard mHealth-related patient data

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  • US Professional News
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Microhospitals offer potential solution to ER services shortages

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  • US Professional News
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CMS gives go-ahead to expansion of Medicare Diabetes Prevention Program

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  • US Professional News
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Medicare and Medicaid lose money by not taking advantage of unique device identifiers, experts say

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New on Univadis

  • Clinical Essentials from Med Sci Monit
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Lung cancer: neoadjuvant chemotherapy + resection improves survival vs chemoradiation alone

Findings support use of preoperative chemotherapy followed by resection whenever possible.

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  • Clinical Essentials from JAMA Oncol
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Ovarian cancer surveillance: CA-125 tests and CT scans routinely used despite unproven benefit

Recommendations to avoid routine CT scans have not been widely adopted into US clinical practice.

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  • Clinical Essentials from JAMA Pediatr
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Teasing out the causes of autism: no link to induction of labor

This large population based study refutes prior speculation.

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  • Clinical Essentials from Pain Res Manag
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Post-op pain after cardiac surgery: parasternal block superior to TENS

This is the first head-to-head comparison in a population undergoing cardiac surgery through median sternotomy.

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  • Clinical Essentials from J Orthop Surg Res
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Total knee arthroplasty: liposome bupivacaine safe, effective for post-op pain control

This is the first meta-analysis of liposomal bupivacaine in patients undergoing total knee arthroplasty.

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  • Clinical Essentials from Cochrane Database Syst Rev
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Cochrane review: insufficient evidence for palivizumab in cystic fibrosis

There are currently no guidelines for palivizumab RSV prophylaxis in infants with cystic fibrosis.

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  • Clinical Essentials from Lancet Respir Med
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COPD: baseline eosinophil counts under 2% bump pneumonia risk

Blood eosinophil counts under 2% have been linked to reduced benefit from inhaled corticosteroids.

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  • Clinical Essentials from MMWR Morb Mortal Wkly Rep.
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Zika: CDC updates guidelines for preventing sexual transmission

Updated CDC guidance now includes both men and women as primary carriers.

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Lipids and CAD: Monthly Essentials July’16
  • Monthly Essentials
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Lipids and CAD: Monthly Essentials July’16

Statins lower risk for coronary artery disease and mortality in familial hypercholesterolemia... 1 in 5 American children and teens have abnormal levels of cholesterol

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  • Clinical Essentials from Am J Obstet Gynecol
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Maternal morbidity highest in low- and high-volume hospitals

More analysis needed to tease out risk factors.

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Acute ischaemic stroke and neuroprotective strategies
  • The Lancet Neurology
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Acute ischaemic stroke and neuroprotective strategies

An update on the status of major ongoing and recently completed RCTs assessing different neuroprotective strategies

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10 modifiable risk factors associated with 90% of the population-attributable risk of strokes
  • The Lancet
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10 modifiable risk factors associated with 90% of the population-attributable risk of strokes

Results from first phase of INTERSTROKE study

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  • Clinical Essentials from J Am Acad Dermatol
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Pediatric melanomas mimic benign skin lesions

Pediatric melanomas often lack traditional ABCDE criteria, highlighting the importance of predictive risk factors.

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  • Clinical Essentials from Int J Clin Oncol
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Urothelial cancer: sarcopenia independently predicts survival

As a biomarker, sarcopenia can be easily evaluated on routine imaging at no extra cost.

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