Recommended on Univadis

  • Clinical Essentials from JAMA
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USPSTF: not enough proof for visual skin cancer screening

US Preventive Services Task Force updates 2009 review but fails to recommend visual exams.

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  • Clinical Essentials from Lancet
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Depression: simplified psychotherapy works just as well

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  • Clinical Essentials from U.S. Food and Drug Administration
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FDA approves lixisenatide to treat type 2 diabetes

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  • Clinical Essentials from PLoS One
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MCRC: how do elderly patients respond to treatment?

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  • Clinical Essentials from Urology
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RCC linked to greater post-op drop in renal function than urothelial carcinoma

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  • Clinical Essentials from Br J Haematol
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First-line DLBCL: BR in elderly, frail patients delivers high response and low survival

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  • Clinical Essentials from Lancet Glob Health
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War on congenital syphilis progressing, but not yet won

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  • Clinical Essentials from J Clin Oncol
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ASCO issues new guidelines for managing chronic pain in cancer survivors

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  • Clinical Essentials from JAMA Cardiol
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Antiplatelet observational studies: validity issues may challenge conclusions

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Professional Essentials

  • Patients Will Be Asking
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Can I get the new HPV vaccine if I got the old one when I was younger?

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  • US Professional News
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When physicians adopt the language of war, do they go to war with those around them?

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  • US Professional News
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CVS and Veterans Affairs lead list of organizations receiving HIPAA complaints

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  • US Professional News
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On-demand health services see rapid growth, gain influx of cash

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  • US Professional News
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Patients are contributing more of their own health data to medical records

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  • US Professional News
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Medicare to test population-health approach to cardiac disease prevention

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New on Univadis

Concussion linked to long-term brain changes in young athletes
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Concussion linked to long-term brain changes in young athletes

Brains of college athletes with prior concussion show physical changes years later.

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Germline mutation in VSIG10L underlie susceptibility to familial Barrett neoplasia
  • JAMA Oncology
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Germline mutation in VSIG10L underlie susceptibility to familial Barrett neoplasia

Functional studies revealed, germline mutation in VSIG10L disrupts esophageal epithelial maturation

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  • Clinical Essentials from Eur Urol
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High-grade prostate cancer: EBRT and radical prostatectomy achieve equivalent survival

Extremely dose-escalated radiation therapy offered optimal systemic control in patients with Gleason 9-10 disease.

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  • Clinical Essentials from Gastroenterol Hepatol
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HBV: NA therapy prevents HCC recurrence, meta-analysis confirms

Despite consensus on improved OS, the impact of NA therapy on recurrence remains controversial.

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  • Clinical Essentials from Pediatr Obes
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Childhood adiposity linked to reduced fertility in women

Women with obesity before the age of 12 y are significantly less likely to achieve pregnancy.

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  • Clinical Essentials from Gastroenterology
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HCV: new DAAs show promising results in phase 2 trials

Clearance rates ranged from 96% to 100% in cirrhotic patients with HCV genotypes 1 and 3.

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Influenza: Monthly Essentials July’16
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Influenza: Monthly Essentials July’16

Influenza vaccination during pregnancy reduces ED visits, hospitalizations for acute respiratory infection... Timely use of oseltamivir has only modest impact on influenza-like illness, hospitalizations

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  • Clinical Essentials from Am J Obstet Gynecol
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Is there a good alternative to transvaginal ultrasound for cervical length?

Cervicometer may be useful as a screening tool when ultrasound technology is not available.

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  • Clinical Essentials from Cell
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Zika virus: new breakthrough may lead to vaccine

Researchers have identified neutralizing monoclonal antibodies that appear to protect mice against infection.

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  • Clinical Essentials from Am J Psychiatry
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Opioid use disorder: is pain a predictor?

Patients with moderate to severe pain should be carefully monitored.

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  • Clinical Essentials from CMAJ
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Type 2 diabetes: influenza vaccination reduces cardiovascular admissions

Findings underscore the importance of flu shots in this high-risk population.

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  • Clinical Essentials from Int J Gynaecol Obstet
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Multiple sclerosis: IVIG reduces postpartum relapse rate

Avoiding the postpartum upswing in MS relapse rates.

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  • Clinical Essentials from J Am Acad Child Adolesc Psychiatry
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Maternal smoking linked to Tourette syndrome, tic-disorder, and ADHD

How strong is the association?

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  • Clinical Essentials from Sleep Med Rev
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Insomnia: internet psychotherapy works, meta-analysis shows

Internet delivery can improve availability and access to cognitive-behavioral therapy for insomnia.

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