Recommended on Univadis

Daratumumab, Bortezomib,  and Dexamethasone for Multiple Myeloma
  • The New England Journal of Medicine
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Daratumumab, Bortezomib, and Dexamethasone for Multiple Myeloma

The addition of daratumumab resulted in longer progression-free survival and a higher rate of response than bortezomib and dexamethasone alone.

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  • The New England Journal of Medicine
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70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

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  • The New England Journal of Medicine
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Inotuzumab Ozogamicin versus Standard Therapy for Acute Lymphoblastic Leukemia

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  • Clinical Essentials from Oncotarget
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HCC: user-friendly nomogram predicts post-resection survival

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  • Clinical Essentials from BMJ Open Diabetes Res Care
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Early short-term intensive insulin induces type 2 diabetes remission

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  • Clinical Essentials from Innovations
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First expert consensus recommendations on sutureless and rapid deployment valves

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  • Clinical Essentials from BMJ
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Pioglitazone and bladder cancer: debunking the myth

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  • Clinical Essentials from Cancer Immunol Immunother
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DLBCL: loss of HLA class II independently linked to adverse PFS

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  • Clinical Essentials from Eur J Cancer
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Early ovarian cancer: lymph node dissection improves survival

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Professional Essentials

  • US Professional News
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EHRs are "shackles" to some physicians

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  • US Professional News
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Women may face unique barriers to care when insured via the ACA exchanges

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  • US Professional News
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Many physicians elect to minimize risk under new MACRA reimbursement models

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  • US Professional News
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Pill organizers may cause seniors more harm than good

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  • Patients Will Be Asking
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How can I increase my job satisfaction?

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  • Patients Will Be Asking
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How can I help my teen lose weight if I'm not supposed to talk about it?

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New on Univadis

Reducing the high cost of prescription drugs in the U.S
  • JAMA
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  • FULLTEXT

Reducing the high cost of prescription drugs in the U.S

Prescription drug costs in the United States continue to rise well above inflation rates and make up an increasingly large share of total health care spending. A new report examines several reasons for these higher prices and also suggests policy changes that could help contain drug costs.

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  • Univadis
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HPV vaccine: do parents support school-entry requirements?

25 US states have proposed laws to require HPV vaccine for school entry, but only 2 have actually passed the legislation.

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  • Univadis
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Post-LT HCV: LDV/SOF yields 96% real-world clearance rate

Results of the largest multicenter real-world study to date.

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  • Clinical Essentials from JAMA Otolaryngol Head Neck Surg
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Major salivary gland cancer: RT tops CRT for survival

Study adds to the knowledge base for treating this rare and heterogenous disease.

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  • Clinical Essentials from BMC Cancer
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Breast cancer: DNA therapy improves DFS in phase 2 trial

Study evaluates the benefit of adding Panagen to chemotherapy in patients with stage II-IV disease.

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  • Clinical Essentials from BMC Cancer
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Gastric cancer: questioning the value of adjuvant chemotherapy

Survival benefit does not achieve significance in patients with locally advanced disease.

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  • Clinical Essentials from Gynecol Oncol
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Cervical cancer: older women equally likely to complete treatment, survive

Study shows no impact of age on completion of chemotherapy/radiation, disease-specific survival.

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  • Clinical Essentials from J Dermatol Sci
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Could topical melatonin be the new sunscreen?

Small randomized study yields promising results.

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  • Clinical Essentials from PLoS One
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Among HIV-positive patients, those treated with HAART have lower prevalence of renal impairment

AIDS progression is more likely than HAART adverse effects to cause renal impairment.

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  • Clinical Essentials from Mov Disord
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Parkinson’s: Smoking, axial impairment, age, cognitive disability all predict dependency

Nearly 100% of study participants dependent within 10 y.

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  • Clinical Essentials from Mov Disord
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Tourette syndrome affects education, income levels – Canadian survey

Young males at the highest risk for Tourette syndrome.

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  • Clinical Essentials from Laryngoscope
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OSA: specific surgery sites improve symptoms

Most previous studies have not teased out the effects on these specific surgical sites.

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  • Clinical Essentials from Diabet Med
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Infection rates rise with hyperglycemia in type 2 diabetes

Hyperglycemia may impair multiple immune pathways, including neutrophil activation and antibody function.

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  • Clinical Essentials from J Bone Miner Res
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Gout: large study fails to find link with nonvertebral fractures

It has been suspected that as a form of inflammatory arthritis, gout might increase osteoporosis and fracture risk.

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