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DLBCL: loss of HLA class II independently linked to adverse PFS

Tumor-infiltrating CD8+ T-cells were reduced in HLA class II samples.

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Pioglitazone and bladder cancer: debunking the myth

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Early ovarian cancer: lymph node dissection improves survival

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Multiple sclerosis: early treatment has long-term benefits

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Does prenatal CHD diagnosis miss the mark?

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More ACHD patients die while waiting for a heart

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Osteoporosis: after fragility fracture, prescriptions that increase fracture risk are rarely modified

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AHA scientific statement on CVD risk and sugar intake in children sets limit

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ACC/AHA vs ATP III: which guideline is better for predicting ASCVD risk?

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Professional Essentials

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Obama Administration seeks to ensure compliance with non-discrimination laws during disaster responses

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EpiPen price hikes may threaten ability of severe allergy sufferers to protect themselves

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JAMA review article investigates causes of high drug prices in the United States

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Integrated care teams may improve health care quality while reducing costs

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How can I be sure my kids get their eye health taken care of?

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Aetna to withdraw from many ACA health insurance exchanges

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New on Univadis

Concussion may increase risk of subsequent musculoskeletal injury
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Concussion may increase risk of subsequent musculoskeletal injury

The authors say the findings may have implications for evaluation and management of concussion injuries.

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  • Clinical Essentials from Vaccine
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Infant vaccinations: do faster injection speeds cut acute pain?

Faster injection may help with certain vaccines, but not others.

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Locally advanced GC: pre-op CRT improves histopathologic response, survival

Histopathologic response is a determining factor in long-term patient outcomes.

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  • Clinical Essentials from Biol Blood Marrow Transplant
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Childhood acute leukemia: late effects highly prevalent, regardless of HSCT donor type

Study compares late effects in children receiving SD, MUD, and UCB transplantation.

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  • Clinical Essentials from Ann Intern Med
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Breast cancer: basing screening frequency on breast density and risk

New study offers guidance for personalized screening intervals.

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Allo-HSCT: high hepatic iron content predicts poor survival

Patients with grade 0 liver iron content lived a median 50 mo longer than those with grade 4.

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Sleep problems may portend suicidal behavior in depressed children

Sleep loss could be an early warning of increased suicide risk.

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MSM requesting HIV postexposure prophylaxis (nonoccupational) have higher risk profile

Consultations for NPEP may be a window of opportunity to discuss HIV preexposure prophylaxis.

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Most children—but not all—outgrow atopic dermatitis

Which children are most likely to outgrow AD?

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Persistently high inflammation in RA associated with chronic kidney disease

What's the connection between RA and CKD?

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HL/NHL: do ferritin levels predict survival after auto-HSCT?

Study links high baseline ferritin levels to increased post-transplant mortality.

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Stroke: cortical cerebral microinfarcts are common, have heterogeneous causes

High field strength MRI has made in vivo detection of cortical CMIs feasible.

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Vitamin D supplementation during pregnancy may decrease the risk for postpartum depression

Postpartum depression is related to maternal and neonatal morbidity.

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Vulnerable pregnacy group: risk factors for domestic violence identified

HIstory of violence and depression are risk factors for DV.

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