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Meningococcal vaccine: lower than expected immunogenicity against outbreak antigens

The unlicensed multicomponent serogroup B vaccine was issued by the FDA in response to an outbreak.

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  • Clinical Essentials from Blood
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R/R HL: single-agent brentuximab vedotin delivers impressive sustained remission

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  • Clinical Essentials from Anesth Analg
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Society of Anesthesia and Sleep Medicine: new OSA/surgery guidelines

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  • Clinical Essentials from Emerg Med J
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Pediatric pneumonia: lung ultrasound diagnosis?

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  • Clinical Essentials from N Engl J Med
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Is physiologic definition of COPD adequate? Expert comment

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  • Clinical Essentials from Efficacy and Mechanism Evaluation
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Cystic fibrosis: novel nonviral gene therapy improves lung function

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  • Clinical Essentials from Eur J Surg Oncol
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Electrochemotherapy: a promising strategy for skin cancer, superficial metastases

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  • Clinical Essentials from Resp Med
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Can exposure to household bleach cause asthma?

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  • Clinical Essentials from BJU Int
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Prostate cancer: expanded primary care role is cost-effective in low to moderate-risk disease

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Professional Essentials

  • Patients Will Be Asking
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How does alcohol cause cancer?

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  • US Professional News
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DOJ: Three individuals allegedly responsible for $1 billion Medicare fraud scheme

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  • US Professional News
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Cyber threats to health care are on the rise, FBI says

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  • US Professional News
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National study shows wide variation in health quality at the community and state level

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  • Patients Will Be Asking
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What if I don’t want you talking to my kid about sex and sexuality?

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How can I keep my backyard chickens from making me sick?

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Multiple sclerosis: improving the accuracy of MRI diagnosis in clinically isolated syndrome

Can accuracy of MRI in clinically isolated syndrome be improved without lowering specificity?

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  • Clinical Essentials from Scand J Prim Health Care
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Substance abuse: lack of follow-up referrals for acute poisonings

A high rate of attendance among patients referred for follow-up suggests a good opportunity for intervention.

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  • Clinical Essentials from Health Technol Assess
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Trapeze trial: generic zolendronic acid is cost-effective in bony mCRPC

The eagerly-anticipated cost-effectiveness data for strontium-89 and zolendronic acid with docetaxel.

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HCV-1: can first-line SMV+PR therapy be safely shortened to 12 wk?

Phase 3 study represents the first assessment of a 12-wk total treatment duration for simeprevir+PR.

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  • Clinical Essentials from Am J Obstet Gynecol
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Marijuana use in pregnancy: a public health issue?

Education about risks of marijuana use during pregnancy needed.

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  • Clinical Essentials from J Am Soc Nephrol
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Maintenance dialysis: cognitive impairment linked to uremic metabolite retention

Further research may determine whether these markers represent modifiable risk factors for uremic cognitive impairment.

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  • Clinical Essentials from Int J Geriatr Psychiatry
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Anxiety, depression linked to comorbidities in older adults

Anxiety and depressive symptoms should be considered when evaluating older adults with multimorbidities.

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  • Clinical Essentials from Eur Addict Res
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Alcohol dependence medications: survey of European Federation for Addiction Societies

Effective treatments to achieve abstinence or curb heavy drinking are underused.

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  • Clinical Essentials from Mov Disord
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Parkinson’s: arm-swing asymmetry may be an early warning sign

Walking diagnosis: a measure of Parkinson’s risk

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  • Clinical Essentials from J Sex Med
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Testosterone: treating late-onset hypogonadism improves bone mineral density

Benefits of testosterone treatment seen in retrospective study of late-onset hypogonadism.

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  • Clinical Essentials from Br J Haematol
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FLT3-ITD AML: posttransplant sorafenib improves survival, reduces relapse

Incidence of GVHD and NRM were comparable with control patients.

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  • Clinical Essentials from Ann Surg
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Hepatectomy for HCC: pure laparoscopic approach appears preferable

Use of laparoscopic hepatectomy for HCC is controversial and especially challenging in patients with cirrhosis.

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COPD: Monthly Essentials July’16
  • Monthly Essentials
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COPD: Monthly Essentials July’16

COPD: respiratory symptoms common in smokers with preserved pulmonary function... Depression decreases COPD maintenance medication adherence in older adults

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  • Clinical Essentials from BMC Pregnancy Childbirth
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Healthy pregnancy habits: educational intervention improves providers' knowledge

Education of healthcare providers can help improve counseling on diet and exercise.

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