Recommended on Univadis

  • Clinical Essentials from J Clin Oncol.
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FL: baseline total metabolic tumor volume predicts early progression

Inferior PFS reported in patients with TMTV > 510 cm3

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  • Clinical Essentials from N Engl J Med
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Early-stage breast cancer: novel 70-gene signature predicts chemotherapy benefit

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  • Clinical Essentials from N Engl J Med
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R/R multiple myeloma: daratumumab-based regimen delivers deep, rapid, and durable response

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  • Clinical Essentials from N Engl J Med
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R/R ALL: single-agent inotuzumab ozogamicin significantly outperforms standard chemotherapy

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  • Clinical Essentials from MMWR Recomm Rep
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Influenza vaccination: updated recommendations for the 2016-17 season

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  • Clinical Essentials from Geriatr Orthop Surg Rehabil
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Knee osteoarthritis: knee replacement does not lead to increased physical activity

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  • Clinical Essentials from J Am Coll Cardiol
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Despite ACC/AHA guideline, many elderly don’t need statins

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  • Clinical Essentials from Stroke
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Afib is linked to transient ischemic attacks as well as ischemic stroke

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  • Clinical Essentials from Int J Urol
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Uro-oncological surgery: fondaparinux noninferior to LMWH

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Professional Essentials

  • Patients Will Be Asking
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Do I need to be worried about bird flu this season?

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  • Patients Will Be Asking
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Is my CPAP machine worthless?

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  • US Professional News
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Consumers may have fewer health insurance options in 2017

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  • US Professional News
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Virtual care clinics may be a paradigm shift for the practice of medicine

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  • US Professional News
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Medicare Part D spending rose significantly in 2014

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  • US Professional News
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Cyber thieves continue to target digital health files

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New on Univadis

Removing grains from the diet can improve certain inflammatory airways disease | ICI
  • Conference Essentials
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Removing grains from the diet can improve certain inflammatory airways disease | ICI

When grain-related foods are reduced in the nutritional pattern, vegetable-related elements tend to increase.

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Fitbit consumer physical activity monitor accurately estimates energy expenditure and step counts | ESC
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Fitbit consumer physical activity monitor accurately estimates energy expenditure and step counts | ESC

The first study to evaluate the validity of three wrist-worn physical-activity devices

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Working outdoors in summer is risk factor for acute myocardial infarction | ESC
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Working outdoors in summer is risk factor for acute myocardial infarction | ESC

In summer the risk vs indoor workers was 2.66, in comparison with retirees 3.35.

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British study: Unnecessary angiography among strategies to guide care of suspected CHD | ESC)
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British study: Unnecessary angiography among strategies to guide care of suspected CHD | ESC)

Evidence from large populations presenting with chest pain finds majority will not have significant obstructive coronary disease.

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Cervical cancer: HIV infection increased the risk of death
  • Journal of Clinical Oncology
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Cervical cancer: HIV infection increased the risk of death

Study compares cervical cancer outcomes by HIV status

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  • Univadis
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Novel TB vaccine: phase 2 trial halted recruitment due to adverse event

The only approved tuberculosis vaccine has varying efficacy for pulmonary disease.

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  • Clinical Essentials from Surg Today
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Colorectal cancer with peritoneal metastasis: palliative resection improves survival

Peritoneal metastasis of colorectal cancer is still associated with poor prognosis.

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  • Clinical Essentials from Urol Oncol
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Prostate cancer: pathologic findings similar for men above and below age 50

Rates of postoperative continence were similar across age groups, but younger men recovered erectile function quicker.

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  • Univadis
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HCV-1: OST and illicit drug use have no impact on LDV/SOF efficacy

Data from the ION trials show no impact on treatment completion, adherence, or HCV clearance rates.

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  • Clinical Essentials from Gastric Cancer
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Gastric cancer: conversion therapy yields good pathologic response, favorable prognosis

Efficacy and safety of conversion therapy when distant metastases are controlled by chemotherapy remain unclear.

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  • Clinical Essentials from MMWR Morb Mortal Wkly Rep
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MMWR: national shifts in adolescent vaccination uptake

HPV vaccination rates still lag behind other teen vaccines, but are improving.

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  • Clinical Essentials from Clin Infect Dis
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HCV: OST has no impact on SOF/VEL efficacy

Data from the ASTRAL trials show no impact on adherence, HCV clearance, or adverse event rates.

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  • Clinical Essentials from Am J Respir Crit Care Med
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Obese kids may have worse asthma due to pattern of lung growth

Why do obese children have worse asthma?

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Dementia: Monthly Essentials August 2016
  • Monthly Essentials
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Dementia: Monthly Essentials August 2016

CCBs lower dementia risk… ACEIs, ARBs, and RASBs also… Handgrip strength, walking speed both predict AD risk.

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