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News

Today’s most essential news for your practice, in time-saving summaries.

FDA approves frontline pembrolizumab for head and neck cancer

Priority review based on data from KEYNOTE-048.

June 24, 2019

Pancreatic NETs: no survival benefit for lymph node dissection

Current guidelines recommend lymph node dissection, but evidence is lacking.

June 24, 2019 -

Ann Surg Oncol

Alcohol underrecognized as a risk factor for breast cancer

Low alcohol literacy is common among mammography attenders and staff.

June 24, 2019 -

BMJ Open

Ovarian cancer: upfront bevacizumab fails improve overall survival in phase 3

Exploratory analysis suggests survival benefit in BRCA subsets.

June 24, 2019 -

J Clin Oncol

Exercise may cut risk for myelodysplastic syndromes

June 24, 2019 -

Cancer Epidemiol Biomarkers Prev

Add-on zoledronic acid shows benefit in neoadjuvant breast cancer

June 24, 2019 -

Ther Adv Med Oncol

Gastric cancer: data fail to support routine chest CT for staging

June 24, 2019 -

Br J Surg

Pediatric achondroplasia: peptide analogue yields increased growth, mild side-effect profile

June 21, 2019 -

N Engl J Med

CKD risk greatest in nondrinkers with high serum uric acid

June 21, 2019 -

Am J Nephrol

Untreated white-coat hypertension is linked to increased mortality, CV events

June 21, 2019 -

Ann Intern Med

Opioid use disorder on the rise among chronic pain patients

June 21, 2019 -

Pain Pract

Long-term catheterization linked to higher comorbidity, UTIs in community-dwelling adults

June 21, 2019 -

BMJ Open

Psoriasis: adalimumab biosimilar therapeutically equivalent in phase 3

June 21, 2019 -

Br J Dermatol

Sudden death can occur in treatment-responsive, benign epilepsy

June 21, 2019 -

Neurology

Antibiotic stewardship program works in ED and urgent-care settings

June 21, 2019 -

Acad Emerg Med

Pregnant patients? Focus Zika conversations on risk

June 21, 2019 -

Matern Child Health J

Bladder cancer: higher lung cancer risk warrants screening

June 21, 2019 -

Clin Lung Cancer

Yogurt may reduce colon cancer risk in men

June 21, 2019 -

Gut

EHA 2019 – Expert Commentary – Pregnancy and family planning: an evaluable option in patients with chronic myeloid leukemia

June 21, 2019

EHA 2019 – Expert commentary – Gene therapy and cellular therapy: the present is bright, the future may be sparkling

June 21, 2019

With comorbid anxiety, T2D costs more

June 21, 2019 -

Diabetes Care

Heart failure ups fracture risk in meta-analysis

June 21, 2019 -

Osteoporos Int

Statins tied to lower risk for stroke after cancer radiotherapy

June 21, 2019 -

J Am Heart Assoc

Does preeclampsia affect risk for maternal infectious morbidity?

June 21, 2019 -

J Matern Fetal Neonatal Med

Renal cancer: limited benefit for nivolumab in brain metastases

June 21, 2019 -

J Clin Oncol

Breast cancer: MRI-based screening tops mammography in women with familial risk

June 21, 2019 -

Lancet Oncol

Meta-analysis evaluates combination contraceptives, metformin in PCOS

June 21, 2019 -

Clin Endocrinol (Oxf)

Pediatric cervical spine injury: many factors are predictive

June 21, 2019 -

Pediatrics

Malnourished IBD patients are almost 3 times likelier to flare

June 21, 2019 -

Dig Liver Dis

Nasopharynx cancer: intensity-modulated radiotherapy best in meta-analysis

June 21, 2019 -

Medicine (Baltimore)

Rectal cancer: 4-12-week surgical delay optimal after short-course radiotherapy

June 21, 2019 -

Br J Surg

Primary prevention of SCD: a guide to the guidelines

June 20, 2019 -

JAMA

Effects of childhood trauma, abuse extend well into older age

June 20, 2019 -

J Am Geriatr Soc

Early NSCLC: segmentectomy yields low recurrence rate at 5 years

June 20, 2019 -

Clin Lung Cancer

Do ASCO, ESMO oncology frameworks measure clinical benefit?

June 20, 2019 -

JAMA Oncol

EHA 2019 – How to manage the toxicity of new agents used in oncohematology

June 20, 2019

EHA 2019 – Advocacy Session – HARMONY Alliance: big data towards a better and faster treatment

June 20, 2019

Physical limitations tied to increased risk for mental health conditions in youth

June 20, 2019 -

Pediatrics

Prostate biopsy: nerve block combination bests standard pain control

June 20, 2019 -

Int J Urol

Methylphenidate is not linked to psychotic events in adolescents

June 20, 2019 -

Lancet Psychiatry

Routine use of tranexamic acid in PPH is cost-effective

June 20, 2019 -

Am J Obstet Gynecol

European measles cases pose risk to US travelers

June 20, 2019 -

Pediatrics

Insulin use predicts worse cerebrovascular outcomes in DM with Afib

June 20, 2019 -

Am Heart J

Biomarker panel predicts memory decline among elders without dementia

June 20, 2019 -

JAMA

DAA triplet highly effective for refractory HCV

June 20, 2019 -

J Hepatol

Head/neck cancer: no benefit for afatinib after definitive chemoradiation

June 20, 2019 -

JAMA Oncol

Brentuximab+AVD delivers excellent response in early nonbulky cHL

June 20, 2019 -

Blood

Psoriasis: cytokine suppression tied to continued response after stopping guselkumab

June 20, 2019 -

J Invest Dermatol

IVF: gonadotrophins similar in amount required to achieve live birth

June 20, 2019 -

Hum Reprod Open

Post-TAVR stroke: uncommon but deadly

June 20, 2019 -

JAMA

Conference Coverage

Essential news from major medical conferences

ADA 2019

San Francisco, California, June 7 - 11

June 11, 2019

ASCO 2019

Chicago, Illinois, May 31 - June 4

June 04, 2019

More Conference Coverage

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

Exploding e-cigarette shatters teenager's jaw

June 21, 2019

If ACA is invalidated, 20 million people will lose insurance: study

June 21, 2019

Primary care needs disruptive changes in training, scope of practice: opinion

June 21, 2019

Amazon might bypass pharmacy benefit managers, upending drug distribution, reimbursement

June 21, 2019

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

Obstructive sleep apnea and the latest devices

Which ones come with a strong recommendation?

June 24, 2019

A tool for predicting appendicitis

June 21, 2019

Image Quiz: Chest pains from an unusual cardiac source

June 20, 2019