Recommended on Univadis

  • Clinical Essentials from J Clin Oncol
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ASCO clinical opinion: 2nd-line hormonal therapy for chemo-naïve CRPC

New ASCO provisional clinical opinion on treating castration-resistant prostate cancer.

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  • Clinical Essentials from J Clin Oncol
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cHL: pembrolizumab delivers impressive response in relapsed/refractory disease

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  • Clinical Essentials from Int J Stroke
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Stroke: how does intra-arterial treatment affect QoL?

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  • Clinical Essentials from Nutrients
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Bone turnover markers unaffected by vitamin D supplements in hypertensive patients

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  • Clinical Essentials from FDA
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FDA approves Rydapt for FLT3-mutated AML

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  • Clinical Essentials from Lancet
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Advanced HCC: nivolumab shows encouraging response rates

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  • Clinical Essentials from Cochrane Database Syst Rev
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Does starting DMTs for a first attack of suspected MS improve outcomes?

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  • Clinical Essentials from PLoS One
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Do medically managed patients with AS have buyers’ remorse?

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  • Clinical Essentials from BJOG
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How should we follow women with hypertensive disease in pregnancy?

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Professional Essentials

  • US Professional News

Cancer hype gives false hope to patients, families

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  • US Professional News

Female physicians make 27% less than men

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  • US Professional News

Practices should maintain policy on abusive behavior by physicians

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  • US Professional News

Chicago trauma physicians, nurses cope with compassion fatigue

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  • Patients Will Be Asking

Why does my heart race when I drink?

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  • Patients Will Be Asking

Is saturated fat that bad?

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New on Univadis

Limited metastatic gastric/gastroesophageal junction cancer: neoadjuvant chemotherapy followed by surgery improve OS
  • JAMA Oncology
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Limited metastatic gastric/gastroesophageal junction cancer: neoadjuvant chemotherapy followed by surgery improve OS

Results from AIO-FLOT3 phase 2 trial provides a rationale for further phase 3 trial

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  • Clinical Essentials from Int J Gynecol Cancer
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ESGO issues guidelines for the management of vulvar cancer

Evidence-based recommendations from the European Society of Gynaecological Oncology.

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  • Clinical Essentials from J Clin Oncol
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Breast cancer: what do patients think of PCP involvement?

First study of its kind to evaluate PCP roles in breast cancer care.

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  • Clinical Essentials from Hum Pathol
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Intestinal type GAC: tumor budding linked to nodal metastasis, recurrence

The association was previously observed in intestinal carcinomas of the colon and esophagus.

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  • Clinical Essentials from J Hepatol
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DAAs for HCV: study shows 5.7% HBV reactivation rate

HCV relapse in 2 patients was followed by HBV suppression.

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  • Clinical Essentials from Crit Care Med
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Polymyxin B hemoperfusion confers survival benefit in some patients with sepsis

For patients with sepsis with intermediate risk for mortality, clinicians may wish to consider polymyxin B hemperfusion

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  • Clinical Essentials from Br J Haematol
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HCV: DAAs safe, effective in patients with β-thalassemia, cirrhosis

Data from the largest study to date.

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Motor function worse in former National Football League players | AAN
  • Conference Essentials
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Motor function worse in former National Football League players | AAN

However, their motor test performances were relatively normal and unrelated to repetitive head impacts.

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  • Clinical Essentials from J Am Heart Assoc
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HIV: TDF linked to lower risk for heart failure

Tenofovir disoproxil fumarate is often used in HIV, despite its association with chronic kidney disease.

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Green Island Fire in 2015 caused mass exposure to hydrofluoric acid and serious medical problems | WADEM
  • Conference Essentials
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Green Island Fire in 2015 caused mass exposure to hydrofluoric acid and serious medical problems | WADEM

Exposure to high concentration hydrofluoric acid can cause profound hypocalcemia, arrhythmias, and multisystem failure.

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  • Clinical Essentials from Am J Obstet Gynecol
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Late preterm steroids most beneficial up to 35 wk

Preventing respiratory complications must be balanced with concerns for future neurodevelopment.

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  • Clinical Essentials from Am J Obstet Gynecol
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Ovarian reserve unaffected with salpingectomy at the time of cesarean delivery

Consider salpingectomy at CD in women desiring sterilization to reduce future risk for ovarian cancer.

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  • Clinical Essentials from J. Trop. Pediatr
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Chikungunya: highly endemic in the Americas, vertical transmission concerns are raised

Case data suggest vertical transmission leading to Chikungunya congenital infections

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  • Clinical Essentials from Am J Resp Crit Care Med
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Acute respiratory distress syndrome: the long-term cost to survivors

Survivors of acute respiratory distress syndrome frequently experience long-term physical, cognitive, and mental health impairments.

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