- Univadis
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ASCO 2017 - Relapsed/refractory diffuse large B-cell lymphoma: JCAR017 achieves high CR rates in phase 1 trial
No severe cytokine release syndrome at the lower dose.
Recommended on Univadis
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ASCO 2017 - Metastatic castration-resistant prostate cancer: indoximod after sipuleucel-T boosts PFSl in phase 2 trial
- Univadis
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ASCO 2017 - Relapsed/refractory multiple myeloma: LCAR-B38M yields 100% ORR in phase 1 trial
- Univadis
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ASCO 2017 - NHL: 82% ORR with axicabtagene ciloleucel in phase 1/2 ZUMA-1 trial
- Univadis
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ASCO 2017 - Advanced SCLC: promising results with nivolumab±ipilimumab
- Univadis
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ASCO 2017 - Melanoma brain mets: nivolumab+ipilimumab deliver promising phase 2 results
- Univadis
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ASCO 2017 - High-risk breast cancer: pembrolizumab+standard therapy improved pathologic complete response rates
- Univadis
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ASCO 2017 - NSCLC: phase 3 study suggests prolonged survival benefit with atezolizumab
- Univadis
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ASCO 2017 - Extensive-stage SCLC after chemotherapy: favorable OS with pembrolizumab in phase 2 trial
Professional Essentials
- US Professional News
Senate health bill includes cuts to Medicaid
- US Professional News
PCPs: fickle millennials may move on
- US Professional News
MACRA reporting eased in proposal
- US Professional News
AMA campaign aimed at easy MIPS compliance
- Patients Will Be Asking
Can I get a "gentle" cesarean?
- US Professional News
American Medical Association delegates push for MOC credit
New on Univadis
- Clinical Essentials from JAMA Intern Med
- 1 comment
CRC: meta-analysis supports diagnostic FIT in high-risk patients
Accuracy for advanced cases is not as good, however.
- Clinical Essentials from Scand J Pain
- 1 comment
THA: local infiltration analgesia tops femoral nerve block for post-op pain
Results of a randomized, double-blind study.
- Clinical Essentials from Arthritis Rheumatol
- 1 comment
RA: elderly patients are getting a lot of opioid prescriptions
Especially if they are black or have back pain.
- Clinical Essentials from Arthritis Care Res (Hoboken)
- 1 comment
RA: fish-eating patients might do better
Clinically significant differences in disease scores in frequent vs infrequent fish eaters.
- Clinical Essentials from JAMA
- no comment
3 of every 100 US adults takes way too much vitamin D
The number overdoing vitamin D has increased since 1999.
- Clinical Essentials from Ann Oncol
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MCRC: less hand-foot syndrome with S-1 vs capecitabine
Data from the phase 3 SALTO trial show reduced incidence, severity.
- Clinical Essentials from MMWR Morb Mortal Wkly Rep
- 1 comment
CDC: chronic Lyme disease treatments tied to serious infections
Overdiagnosis of chronic Lyme based on clinical suspicion alone is a growing problem.
- Clinical Essentials from Chest
- 1 comment
Chest Expert Cough Panel: recommendations on chronic cough in children
The most common etiologies vary according to age and location.
- Clinical Essentials from Clin Gastroenterol Hepatol
- 1 comment
HCV: pre-LT DAA therapy most cost effective with lower MELD
Posttransplant treatment is more cost effective/saving with MELD over 22.
- Clinical Essentials from AJNR Am J Neuroradiol
- 1 comment
Stroke: CTA angiography tops noncontrast CT for predicting EVT outcomes
Data supports use of CTA-SI ASPECTS, which is not currently considered in EVT-eligibility guidelines.
- Clinical Essentials from BMJ Open
- 1 comment
Depression: 2nd generation antidepressants, CBT are best bets
Analysis of 19 systematic reviews.
- Clinical Essentials from JAMA Cardiol
- 1 comment
TAVR: nearly 1 in 10 procedures in the US are off-label
Off-label indications most commonly include severe aortic or mitral regurgitation.
- Clinical Essentials from J Diabetes Sci Technol
- no comment
How accurate are diabetes alert dogs?
Accuracy varies widely among individual dogs.
- Clinical Essentials from Am Health Drug Benefits
- 1 comment
Prostate cancer: lower CNS risk with abiraterone vs enzalutamide, chemotherapy
Reduced risk for CNS effects was independent of metastases.