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News

Today’s most essential news for your practice, in time-saving summaries.

Cannabis in pregnancy: meta-review expands on surgeon general's data

Clinicians should continue to warn against prenatal use.

September 23, 2019 -

BJOG

Pediatric severe sepsis: continuous renal replacement linked to lower mortality

Significant improvement in all-cause, ARDS-related death in propensity-matched comparison.

September 23, 2019 -

Crit Care Med

Youngest in class more likely to have depression, intellectual disability, ADHD

Study is among first to examine younger relative age and mental health diagnoses.

September 23, 2019 -

JAMA Pediatrics

Polypill for BP and cholesterol control beats usual care in some populations

In socioeconomically vulnerable minority populations, the combo shows promise.

September 23, 2019 -

N Engl J Med

Pneumonia: dental care cuts recurrence risk for neurologically impaired children

September 23, 2019 -

Pediatrics

FDA approves expanded indication for 2 HIV therapies

September 23, 2019 -

Merck

FDA approves apalutamide for metastatic prostate cancer

September 23, 2019

Timing matters: early palliative care boosts lung cancer survival

September 23, 2019 -

JAMA Oncol

Night-owl adolescent girls may have increased risk for adiposity

September 23, 2019 -

JAMA Pediatr

Cushing's syndrome: levoketoconazole shows benefit in phase 3 trial

September 23, 2019 -

Lancet Diabetes Endocrinol

Are adolescents who use LARC at increased risk for chlamydia infection?

September 23, 2019 -

J Pediatr Adolesc Gynecol

Cancer: prior antibiotics cut response to immune checkpoint inhibitors

September 23, 2019 -

JAMA Oncol

R/R CLL: ibrutinib maintains efficacy advantage at 6 years

September 23, 2019 -

Am J Hematol

Esophageal cancer: radiotherapy boost improves local control, survival

September 23, 2019 -

JAMA Oncol

Apatinib shows benefit in heavily pretreated small-cell lung cancer

September 23, 2019 -

Br J Cancer

Breast cancer survival 18% poorer in men than women

September 23, 2019 -

JAMA Oncol

EASD 2019 — Liraglutide reduces insulin dose in newly diagnosed T1D

September 23, 2019

EASD 2019 — PEX168 leads to sustained reductions of HbA1c in uncontrolled T2D

September 23, 2019

EASD 2019 — Ultra rapid lispro features faster absorption in T1D

September 23, 2019

EASD 2019 — Dance 501 insulin inhalation: more rapid onset than insulin lispro

September 23, 2019

ESMO 2019 Preview

September 23, 2019

Risk-based testing insufficiently identifies congenital syphilis

September 20, 2019 -

Pediatrics

Syphilis testing suboptimal among men who have sex with men

September 20, 2019 -

J Epidemiol Glob Health

Psoriasis: serum ustekinumab levels correlate with clinical response

September 20, 2019 -

JAMA Dermatol

Linagliptin noninferior to glimepiride for cardiovascular risk in early T2D

September 20, 2019 -

JAMA

AAN calls for annual cognitive testing in elders

September 20, 2019 -

Neurology

Which lipid marker shows the strongest tie to CVD risk reduction?

September 20, 2019 -

Circulation

FDA approves pembrolizumab/lenvatinib for advanced endometrial cancer

September 20, 2019

Guideline review: diagnosis and management of pancreatic cysts

September 20, 2019 -

Nat Rev Gastroenterol Hepatol

EASD 2019 — Semaglutide improves glycemic control and BMI better than liraglutide in T2D

September 20, 2019

Subdural hematoma risk higher in parturients with postdural puncture headache

September 20, 2019 -

JAMA Neurol

Adjuvant ovarian suppression ups survival in premenopausal breast cancer

September 20, 2019 -

J Clin Oncol

EASD 2019 — Liraglutide + metformin improves glucose control in children, adolescents with T2D

September 20, 2019

Many cancer drugs work independently of their reported targets

September 20, 2019 -

Sci Transl Med

Comorbid opioid use disorder ups suicide risk in veterans with depression or alcohol use

September 20, 2019 -

Psychol Med

COPD exacerbations: what causes antibiotic treatment failure?

September 20, 2019 -

BMJ Open Resp Res

Crohn's: Cochrane review unclear on best way to maintain remission after surgery

September 20, 2019 -

Cochrane Database Syst Rev

Adding memantine to escitalopram boosts cognitive function in depressed elders

September 20, 2019 -

Am J Geriatr Psychiatry

Acute gastroenteritis: ondansetron prescription doesn’t reduce return visits

September 20, 2019 -

Pediatr Emerg Care

DLBCL: likelihood of 10-year survival increases with time from transplant

September 20, 2019 -

Biol Blood Marrow Transplant

Oropharynx cancer: HPV status predicts survival after incomplete radiotherapy

September 20, 2019 -

Oral Oncol

EASD 2019 — Tirzepatide leads to favorable changes in HbA1c after several dose escalations

September 20, 2019

EASD 2019 — T1D: ADO09 reduces postprandial glucose and leads to slower gastric emptying than lispro

September 20, 2019

Heart infections related to drug abuse doubled in 14 years

September 19, 2019 -

J Am Heart Assoc

Pediatric daytime urinary incontinence: Cochrane review finds no clearly best treatment

September 19, 2019 -

Cochrane Database Syst Rev

Diabetes: 2-step testing algorithm best for screening psychiatric inpatients

September 19, 2019 -

PLoS One

COPD: breathing exercises yield multiple benefits in meta-analysis

September 19, 2019 -

Ann Rehabil Med

Vaping illness: FDA launches a criminal investigation

September 19, 2019 -

CDC

Fast MRI is feasible, accurate for pediatric head injury

September 19, 2019 -

Pediatrics

Right-sided colon cancer: recurrence rates favor complete mesocolic excision

September 19, 2019 -

Lancet Oncol

Conference Coverage

Essential news from major medical conferences

EASD 2019

Barcelona, Spain, September 16-20, 2019

WCLC 2019

Barcelona, Spain, September 7-10, 2019

More Conference Coverage

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

Should your practice text message with patients?

September 23, 2019

Climate change isn't just an issue, it's an emergency: AMA grand rounds

September 23, 2019

Women physicians and burnout: what organizations can do

September 23, 2019

Amid value-based care shift, hospitals rethink board members' duties

September 23, 2019

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

Lesions and MS progression

What’s the relationship?

September 24, 2019

Etiology of true hyperthyroidism

September 23, 2019

CDC guidelines for hepatitis A treatment

September 20, 2019