Recommended on Univadis

  • Clinical Essentials from J Hepatol.
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HCV: DAA retreatment 96% successful after first-line failure

Data from a real-world study of patients failing NS5A-based regimens.
  • Clinical Essentials from N. Engl. J. Med
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GLE/PIB is safe, effective for HCV with advanced CKD
  • Clinical Essentials from MMWR Morb Mortal Wkly Rep
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CDC issues guidance on caring for infants with congenital Zika
  • Clinical Essentials from Int J Radiation Oncol
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Prostate cancer: post-RT PSA bounce a sign of survival?
  • Clinical Essentials from J Am Acad Dermatol
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NCDB analysis: how does surgical timing affect melanoma survival?
  • Clinical Essentials from J R Soc Med
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CBT reduces repeat suicide risk
  • Clinical Essentials from Fam Pract
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PPIs tied to 42% increased risk for CKD
  • Clinical Essentials from Eur Urol
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Prostate cancer: abiraterone, docetaxel similarly effective with ADT
  • Clinical Essentials from J Clin Oncol
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Breast cancer: new ASCO guidelines include BMA dosing intervals

Professional Essentials

  • Patients Will Be Asking

Will sugar give me cancer?
  • US Professional News
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California gender can now be nonbinary
  • US Professional News
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Medical practices hard-hit by Hurricane Harvey
  • US Professional News
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Jail for 3 NY physicians in lab bribery scheme
  • US Professional News
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Physicians can help patients avoid treatment-choice regret
  • Patients Will Be Asking

Am I exercising too much?

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New on Univadis

  • Clinical Essentials from Cancer
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Metastatic melanoma: add-on everolimus fails to improve CPB outcomes

Data from a phase 2 randomized trial of combination carboplatin-paclitaxel-bevacizumab.
  • Clinical Essentials from Arthritis Care Res
  • 1 comment

RA: watch out for signs of COPD

The disease may arguably be considered a complication of rheumatoid arthritis.
  • Clinical Essentials from Heart Rhythm
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MRI risk looks low with legacy pacemakers, abandoned leads

No myocardial damage detected based on biomarker measures.
  • Clinical Essentials from International Journal of COPD
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Beta-blockers are underprescribed in COPD

Yet they have a good safety profile and beneficial effect.
No strategy predominates managing eosinophilic esophagitis | WCG
  • Conference Essentials
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No strategy predominates managing eosinophilic esophagitis | WCG

Patients maintained on a PPI were just as likely as those off PPI to remain symptomatic.
Many inpatients with PE and GH undergo endoscopy with low mortality | WCG
  • Conference Essentials
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Many inpatients with PE and GH undergo endoscopy with low mortality | WCG

Association between endoscopy and lower mortality persists when controlled for critical illness and condition upon admission.
Antimicrobials and antiepileptics leading causes of pediatric drug-induced liver injury | AASLD
  • Conference Essentials
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Antimicrobials and antiepileptics leading causes of pediatric drug-induced liver injury | AASLD

The top five implicated agents were minocycline, valproate, azithromycin, and isoniazid.
Neurological Disorders Vitals for October 2017
  • Vitals
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Neurological Disorders Vitals for October 2017

Hypothermia for TBI? | Antidiabetics and dementia risk | Individualizing PML risk assessment in MS | No benefit with O2 supplementation in stroke.
  • Clinical Essentials from Int J Clin Pract
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Exenatide may improve glycemia in poorly controlled type 2 diabetes

Exenatide also promotes weight loss and may reduce blood pressure.
  • Clinical Essentials from Breast Cancer Res Treat
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Breast cancer: high serum selenium predicts longer survival

Selenium supplementation may be considered for patients with low selenium levels.
  • Clinical Essentials from Psychol Med
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CBT beats relaxation therapy for some anxiety disorders

New studies since last meta-analysis shift conclusions for some conditions.
  • Clinical Essentials from PLoS ONE
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Coordinated care models promising in opioid use disorder

Systematic review finds patterns in treatment that work.
  • Clinical Essentials from Aliment Pharmacol Ther
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Treating Crohn’s disease with golimumab

Retrospective analysis finds safety and efficacy.
  • Clinical Essentials from J Eur Acad Dermatol Venereol
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Psoriasis: is apremilast safe and effective in real-world practice?

Real-world data on apremilast efficacy are scarce.
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