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News

Today’s most essential news for your practice, in time-saving summaries.

ESMO 2018 – Global health status, quality of life data favour talazoparib in patients with triple negative breast cancer and BRCA1/2 mutations

Women with triple negative advanced breast cancer and BRCA1/2 mutations in the EMBRACA trial had better QoL on talazoparib vs physician’s choice...

October 21, 2018

ESMO 2018 – The value of adding bevacizumab to carboplatin/pegylated liposomal doxorubicin when treating recurrent ovarian cancer

A new combination regimen based on the three drugs has been shown to provide a significant benefit in progression-free survival compared to...

October 21, 2018

ESMO 2018 – Can advances in metastatic NSCLC be transferred to early-stage disease?

Early-stage NSCLC patients may benefit from immunotherapy and combination approaches

October 21, 2018

ESMO 2018 – Using cabazitaxel before androgen receptor therapy may maximise clinical benefit in poor prognosis mCRPC

Trial reports effect of treatment sequence and prognostic value of circulating tumour DNA

October 21, 2018

ESMO 2018 – Reduced mortality, relapses for sarcoma patients in French reference centre

October 21, 2018

ESMO 2018 – Adding ribociclib to fulvestrant maintains quality of life in advanced breast cancer

October 20, 2018

ESMO 2018 – Adding radium-223 to abiraterone associated with poorer outcomes in mCRPC

October 20, 2018

ESMO 2018 – One in six premenopausal breast cancer patients inadequately adherent to tamoxifen after one year

October 20, 2018

ESMO 2018 – Tepotinib+gefitinib, a promising combination therapy in MET+/EGFR-mutant non-small cell lung cancer

October 20, 2018

ESMO 2018 – Synthetic peptides hit three targets simultaneously in recurrent glioblastoma

October 20, 2018

5-FU adds benefit to triamcinolone for keloids, hypertrophic scars

October 19, 2018 -

Burns

Thyroid ultrasound tied to increased diagnosis of low-risk cancer

October 19, 2018 -

J Clin Endocrinol Metab

Abortion "reversal" legislation and science clash

October 19, 2018 -

N Engl J Med

Aspirin ineffective for preventing dementia, disability in healthy older adults

October 19, 2018 -

N Engl J Med

Rapid opt-out HIV screening boosts uptake in young people

October 19, 2018 -

Pediatrics

Depression: adjunctive atypical antipsychotics have limited use

October 19, 2018 -

Bipolar Disord

Structural brain abnormalities seen in prediabetes

October 19, 2018 -

Diabetes Care

HLA genotyping isn’t useful for celiac screening in T1D

October 19, 2018 -

Arch Dis Child

TKA: aspirin, other anticoagulants similar for VTE prevention

October 19, 2018 -

JAMA Surg

Advanced melanoma: adding ziv-aflibercept to IL-2 boosts PFS

October 19, 2018 -

Cancer

Bladder cancer: no survival advantage for extended vs limited LND in German study

October 19, 2018 -

Eur Urol

3D screening mammography detects 34% more breast cancers

October 19, 2018 -

Lancet Oncol

GOP senator sought "brain frequency" treatment for vets

October 19, 2018

Abuse affects a woman's risk for preterm delivery, low-birth-weight children

October 19, 2018 -

BMC Pregnancy Childbirth

Preeclampsia is a risk factor for Alzheimer's, other dementias

October 19, 2018 -

BMJ

Naloxone for opioid-exposed newborns: 5 years, 1 opioid epidemic, nothing has changed

October 19, 2018 -

Cochrane Database Syst Rev

Ibuprofen does not impair semen quality

October 19, 2018 -

J Assist Reprod Genet

Opioid, benzodiazepine misuse tied to suicidal thinking in elders

October 19, 2018 -

Int J Geriatr Psychiatry

Cirrhosis: opioid prescribing on the rise among veterans

October 19, 2018 -

Clin Gastroenterol Hepatol

CRC screening boosted with FBT outreach, patient navigators

October 19, 2018 -

JAMA Intern Med

R/R CLL/SLL: updated results for the phase 3 HELIOS study

October 19, 2018 -

Leukemia

Postmastectomy RT: chest wall symptoms affect QoL in UK SUPREMO

October 19, 2018 -

Lancet Oncol

HCV: can serum markers replace TE for estimating fibrosis, cirrhosis?

October 19, 2018 -

J Viral Hepat

Hospital says late endocrinologist may have abused patients

October 19, 2018

Apple pursuing patient monitoring beyond its watch EKG

October 19, 2018

IGF-1 mimetic shows promise in spinal and bulbar muscular atrophy

October 19, 2018 -

Lancet Neurol

AAN scrutinizes evidence for nusinersen in SMA

October 19, 2018 -

Neurology

Revisiting brachytherapy for multilayer DES restenosis

October 19, 2018 -

Circ Cardiovasc Interv

Seat belt sign’s position matters

October 19, 2018 -

Emerg Med Australas

Carpal tunnel syndrome could signal amyloid heart disease

October 19, 2018 -

J Am Coll Cardiol

IBD tied to risks for lymphoma, biliary cancer — but not CRC

October 19, 2018 -

Am J Gastroenterol

Lung cancer surgery: lymphopenia on postoperative day 1 tied to POP

October 19, 2018 -

PLoS One

Practice Changer: a GLP1-RA stands out from others in meta-analysis

October 19, 2018 -

Christopher Rawlings, MD

Schizophrenia: cariprazine compared with other antipsychotics

October 18, 2018 -

Neuropsychiatr Dis Treat

Reminders help in DM management, if patients read them

October 18, 2018 -

Am J Manag Care

Alzheimer's disease: opioid use tied to higher risk for hip fracture

October 18, 2018 -

Pain

Yes, treating stage 1, low-risk hypertension offers benefits

October 18, 2018 -

Hypertension

AGA issues new guidelines for opioid-induced constipation

October 18, 2018 -

Gastroenterology

Pediatric cardiac arrest: hypothermia does not improve outcomes

October 18, 2018 -

Resuscitation

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

Hospital says late endocrinologist may have abused patients

October 19, 2018

GOP senator sought "brain frequency" treatment for vets

October 19, 2018

Apple pursuing patient monitoring beyond its watch EKG

October 19, 2018

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

New evidence for effects of ART

Long-term outcomes?

October 22, 2018

A cochlear migraine?

October 19, 2018

Image Quiz: Obese man with HTN, dyspnea on exertion, and heart palpitations

October 18, 2018