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News

Today’s most essential news for your practice, in time-saving summaries.

FDA issues warning for CDK 4/6 inhibitors in breast cancer

Rare but severe cases of lung inflammation reported.

September 19, 2019 -

FDA

Vaping illness: FDA launches a criminal investigation

530 cases reported, clinicians urged to work with state, federal officials.

September 19, 2019 -

CDC

Fast MRI is feasible, accurate for pediatric head injury

Nearly 93% sensitivity relative to CT.

September 19, 2019 -

Pediatrics

Right-sided colon cancer: recurrence rates favor complete mesocolic excision

A population-based cohort study of 5-year outcomes.

September 19, 2019 -

Lancet Oncol

Ibrutinib: invasive fungal disease more common than expected in CLL, NHL

September 19, 2019 -

Mycoses

Cannabis: what brings users to the ED?

September 19, 2019 -

Clin Toxicol (Phila)

Recurrent ovarian cancer: extending platinum-free interval yields poorer survival

September 19, 2019 -

Gynecol Oncol

Nasopharynx cancer: marker combination boosts prognostic value in IMRT era

September 19, 2019 -

Cancer Med

Early NSCLC: academic/research programs offer best chance at survival

September 19, 2019 -

Cancer

EASD 2019 — Dapagliflozin + insulin beats insulin alone for glycemic control in T1D

September 19, 2019

EASD 2019 — Sotagliflozin + insulin superior to insulin alone for glycemia in T1D

September 19, 2019

EASD 2019 — Faster insulin aspart with degludec provides earlier postprandial glucose change

September 19, 2019

EASD 2019 — Once-weekly semaglutide beats canagliflozin for T2D control in metformin-treated patients

September 19, 2019

Breast cancer: NACT delay does not appear to affect survival

September 19, 2019 -

Breast J

Low back pain: joint guidelines from US Departments of Veterans Affairs, Defense

September 18, 2019 -

J Gen Intern Med

Beta blockers fail to show analgesic effect in knee osteoarthritis

September 18, 2019 -

Osteoarthritis Cartilage

Anticoagulants in Afib: adherence among elders reduces stroke risk by 40%

September 18, 2019 -

Am J Cardiovasc Drugs

Metformin favored, newer drugs underutilized in T2DM with CKD

September 18, 2019 -

J Diabetes Complications

In utero exposure to maternal anemia is linked to neurodevelopmental disorders

September 18, 2019 -

JAMA Psychiatry

Sepsis: study supports blood cultures before empirical antibiotics

September 18, 2019 -

Ann Intern Med

Vestibular symptoms often flag serious problems

September 18, 2019 -

J Neurol

Exclusive breastfeeding during pregnancy linked to increased miscarriage risk in some groups

September 18, 2019 -

Perspect Sex Reprod Health

Stage III colon cancer: shorter oxaliplatin-based adjuvant therapy cuts neuropathy, not efficacy

September 18, 2019 -

JAMA Oncol

H pylori eradication tied to durable reduction in gastric cancer incidence, death

September 18, 2019 -

BMJ

Shorter antibiotic course noninferior, preferable for gram-negative bacteremia

September 18, 2019 -

Clin Infect Dis

Nonclassic 21-hydroxylase deficiency tied to cortisol, aldosterone secretion issues

September 18, 2019 -

J Clin Endocrinol Metab

Mesial temporal lobe epilepsy: study clarifies risk factors for drug resistance

September 18, 2019 -

Postgrad Med

Resected NSCLC: study puts 10-year risk for second primary at 20%

September 18, 2019 -

Lung Cancer

Nilotinib shows efficacy in pediatric chronic-phase Ph+ CML

September 18, 2019 -

Blood

Nivolumab: real-world outcomes, prognostic factors in head/neck cancer

September 18, 2019 -

Cancers (Basel)

Melanoma: proteomics identifies responders to immunotherapy

September 18, 2019 -

Cell

For CVD, additive therapies are tied to reduced mortality, costs

September 17, 2019 -

Institute for Clinical and Economic Review

Are you going along with the off-label drug use trend in pediatrics?

September 17, 2019 -

Pediatrics

Update: HCV-infected donor kidneys functioning well at 1 year

September 17, 2019 -

J Am Soc Nephrol

Patient perceptions often diverge from T2D guidelines

September 17, 2019 -

JAMA Intern Med

Actinic keratoses: modified PDT regimen reduces pain without compromising efficacy

September 17, 2019 -

J Am Acad Dermatol

Obstructive sleep apnea tied to doubled risk for affective disorders

September 17, 2019 -

JAMA Otolaryngol Head Neck Surg

CDC opens Emergency Operations Center in response to vaping illness

September 17, 2019 -

CDC

Dementia: donepezil tied to doubled rhabdomyolysis risk

September 17, 2019 -

CMAJ

Debunking old wives' tales: can intercourse induce labor?

September 17, 2019 -

J Sex Med

HER2+ breast cancer: mastectomy tops BCS in the absence of trastuzumab

September 17, 2019 -

Cancer Manag Res

Hypertensive CKD: adjunct patiromer allows persistent spironolactone use

September 17, 2019 -

Lancet

FDA warns of low-level NDMA in some ranitidine products

September 17, 2019 -

U.S. Food and Drug Administration

HPV vaccine: weak communication style tied to lower uptake

September 17, 2019 -

Pediatrics.

E-cigarette use during pregnancy is associated with small for gestational age

September 17, 2019 -

Tob Induc Dis

Please ignore

September 17, 2019

Single-question ED tool disappoints as a mortality predictor

September 17, 2019 -

JAMA Netw Open

Low-income subsidies tied to greater uptake of lung cancer therapy

September 17, 2019 -

J Natl Cancer Inst

Advanced HCC: large cohort backs promise of frontline TACE+radiation

September 17, 2019 -

Radiother Oncol

Delayed treatment for head/neck cancer tied to poor outcomes

September 17, 2019 -

JAMA Otolaryngol Head Neck Surg

Conference Coverage

Essential news from major medical conferences

EASD 2019

Barcelona, Spain, September 16-20, 2019

WCLC 2019

Barcelona, Spain, September 7-10, 2019

More Conference Coverage

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

EHRs ought to warn patients what things will cost: opinion

September 19, 2019

EHRs document more actions than actually occur in a patient encounter

September 19, 2019

Doctors with substance-use disorders are often barred from evidence-based treatment

September 19, 2019

Most clinicians don't screen for social determinants of health, despite guidelines

September 19, 2019

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

Image Quiz: Another obese patient with back pain?

What is the best next step for this patient with a 4-week history of increasing low back pain and bilateral lumbar paresthesia?

September 19, 2019

Kids + this = more risk for TBI?

September 18, 2019

Googling before a medical visit

September 17, 2019