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News

Today’s most essential news for your practice, in time-saving summaries.

Breast cancer survivors face excess risk for second primary cancer in SEER analysis

Second primary tumors may be driven by chemotherapy exposure and carry a poorer prognosis.

March 25, 2019 -

Int J Clin Oncol

Node+ rectal cancer: watchful waiting OK after nCRT complete response

Similar 5-year distant metastasis-free survival vs node-negative patients.

March 25, 2019 -

Dis Colon Rectum

Early NSCLC: post-SBRT chemotherapy tied to poorer survival

For larger tumors, survival was similar with and without ACT.

March 25, 2019 -

Lung Cancer

Merkel cell carcinoma: study identifies predictors of positive SLN

Positive sentinel lymph nodes are associated with poorer survival.

March 25, 2019 -

J Am Acad Dermatol

R/R MM: heavily pretreated patients respond well to isatuximab combination

March 25, 2019 -

Blood

CRC liver metastasis: when is R1 resection adequate?

March 22, 2019 -

Eur J Surg Oncol

CRPC: SBRT shows benefit in oligoprogressive disease

March 22, 2019 -

World J Urol

HCV GT 1-3: GLE/PIB clearance rate tops 99% in advanced CKD

March 22, 2019 -

Aliment Pharmacol Ther

EU cancer deaths projected to continue declining in 2019

March 22, 2019 -

Ann Oncol

Central NSCLC: SBRT yields good outcomes in meta-analysis

March 22, 2019 -

Clin Lung Cancer

HNSCC: advanced lung cancer inflammation index shows prognostic value in Austrian study

March 22, 2019 -

Eur Arch Otorhinolaryngol

Elderly AML: intensive chemotherapy, decitabine offer similar OS

March 22, 2019 -

Clin Lymphoma Myeloma Leuk

Younger age at puberty tied to higher MS risk in women

March 21, 2019 -

Neurology

Laparoscopic decortication is durable, safe, effective for renal cysts: meta-analysis

March 21, 2019 -

Urol Int

Pediatric psoriasis: ustekinumab tops other biologics for drug survival

March 21, 2019 -

J Eur Acad Dermatol Venereol

FDA approves first drug specifically for postpartum depression

March 21, 2019 -

FDA News Release

CF: higher childhood BMI is linked to lower adult transplantation risk

March 21, 2019 -

Lung

IBD: outcomes are similar with low- vs high-dose methotrexate

March 21, 2019 -

J Crohns Colitis

Immediate vs delayed angiography: comparable outcomes after non-STEMI cardiac arrest

March 21, 2019 -

N Engl J Med

Infections tied to increased risk for Sjögren's syndrome

March 21, 2019 -

J Intern Med

Phone-based developmental screening feasible, could lower access barriers

March 21, 2019 -

Pediatrics

Heart care guidelines rarely backed by solid evidence

March 21, 2019 -

JAMA

ESMO updates guidelines for pancreatic cancer

March 21, 2019 -

European Society for Medical Oncology

Dapagliflozin reduces adverse CV outcomes with T2D and prior MI

March 21, 2019 -

Circulation

RA: synthetic DMARDs tied to higher cardiovascular risk than TNF inhibitors

March 21, 2019 -

Arthritis Care Res (Hoboken)

Prostate cancer: test predicts abiraterone, enzalutamide response

March 21, 2019 -

J Clin Oncol

HCV-1/2: 8 weeks of GLE/PIB 99% effective across 6 trials

March 21, 2019 -

J Gastroenterol

Nonfunctional pituitary adenoma: tumor size predicts hypopituitarism incidence, severity

March 21, 2019 -

World Neurosurg

KOA: intra-articular trans-capsaicin relieves walking pain in TRIUMPH

March 21, 2019

Hyperglycemic DM crises: moderate-insulin therapy linked to better outcomes

March 21, 2019 -

Crit Care Med

Can’t-miss studies from ACC 2019

March 21, 2019

Pesticides and NHL: risk is subtype- and chemical-specific

March 21, 2019 -

Int J Epidemiol

NSCLC: post-SABR corticosteroids tied to poorer survival

March 21, 2019 -

Clin Lung Cancer

PTC: study identifies predictors of lateral and skip metastasis

March 21, 2019 -

Surgery

Breast cancer: patients fare better after lumpectomy vs mastectomy

March 21, 2019 -

Breast Cancer Res Treat

Timing improves PVR for evaluating bladder outlet obstruction

March 20, 2019 -

Urol J

Actinic keratosis: halving PDT duration reduces pain but not efficacy

March 20, 2019 -

J Eur Acad Dermatol Venereol

Deferoxamine found disappointing in intracerebral hemorrhage

March 20, 2019 -

Lancet Neurol

Osteoporosis: intramuscular neridronate raises BMD in 6-year study

March 20, 2019 -

Int J Endocrinol

DOT fertility app: does it work?

March 20, 2019 -

Eur J Contracept Reprod Health Care

More youth are visiting the ED for psychiatric problems

March 20, 2019 -

Pediatrics

Mycoplasma genitalium in MSM: 84% of asymptomatic cases are macrolide-resistant

March 20, 2019 -

Emerging Infect Dis

ACC/AHA 2019 guidelines highlight patient collaboration in CVD prevention

March 20, 2019 -

Circulation

Pocket guidelines: pediatric GERD management

March 20, 2019 -

JAMA Pediatr

HBV: daily aspirin therapy is tied to 29% lower HCC risk

March 20, 2019 -

JAMA Intern Med

ACC 2019—Sacubitril/valsartan shows benefit over enalapril in acute HF

March 20, 2019

ACC 2019—ACC/AHA update CVD primary prevention guidelines

March 20, 2019

Adding ultrasound to mammogram may do more harm than good

March 20, 2019 -

JAMA Intern Med

mCRPC: PROSTVAC fails to meet OS endpoint in phase 3 study

March 20, 2019 -

J Clin Oncol

Canagliflozin reduces HF risk, regardless of EF status

March 20, 2019 -

Circulation

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

More physicians are participating in Medicare advanced payment models than expected

March 21, 2019

Immigration exam puts physicians in tough spot

March 21, 2019

Kentucky governor deliberately exposed his 9 children to chickenpox

March 21, 2019

Study finds subtle pro-fentanyl message in CME module

March 21, 2019

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

Motility testing in functional dyspepsia

What does the guideline suggest?

March 25, 2019

Corticosteroids in sepsis

March 22, 2019

Image Quiz: What did the gastroenterologist find on this CT?

March 21, 2019