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News

Today’s most essential news for your practice, in time-saving summaries.

Which DM patients derive CV benefit from intensive lifestyle modification?

In the Look AHEAD trial, some patients benefited, some didn’t, and some were harmed.

August 19, 2019 -

Diabetes Care

HIV: late mortality from cryptococcosis remains a concern

Efforts to improve virological suppression are essential.

August 19, 2019 -

J Acquir Immune Defic Syndr

Childhood IBD tied to excess risk for psychiatric disorders, suicide attempt

Risk was high for specific disorders and persisted for more than 5 years.

August 19, 2019 -

JAMA Pediatr

“Push fast, push hard, don’t stop”: optimal compression rate and depth during CPR

Findings pinpoint 107 compressions a minute to almost 5 cm depth as the sweet spot.

August 19, 2019 -

JAMA Cardiol

Pediatric croup: no clear winner in dexamethasone vs prednisolone trial

August 19, 2019 -

Pediatrics

Gemcitabine-eribulin offers an alternative in metastatic urothelial cancer

August 19, 2019 -

J Clin Oncol

Melanoma: dual BRAF/MEK inhibition tied to greater cardiovascular risk

August 19, 2019 -

JAMA Netw Open

3D mammogram shows advantage across breast density, age groups

August 19, 2019 -

Radiology

Gastric cancer: laparoscopic vs open total gastrectomy

August 19, 2019 -

Ann Surg Oncol

Primary biliary cholangitis worsens within 5 years in almost half of cases

August 19, 2019 -

Clin Gastroenterol Hepatol

Psoriasis tied to excess mortality risk in NHANES analysis

August 19, 2019 -

J Am Acad Dermatol

FDA approves third "tissue agnostic" cancer drug

August 19, 2019 -

FDA

Calculator developed to predict failed IOL with high BMI

August 19, 2019 -

Obstet Gynecol

Use of prophylactic cranial irradiation drops sharply in SCLC

August 19, 2019 -

JAMA Netw Open

Prehospital thrombolysis for OHCA with PE: better survival, unimproved neurological outcomes

August 19, 2019 -

Chest

Subclinical hypothyroidism: levothyroxine reduces pregnancy loss in meta-analysis

August 19, 2019 -

Arch Gynecol Obstet

T2DM: metformin beneficial for comorbid asthma

August 19, 2019 -

Ann Am Thorac Soc

Hematologic malignancies: CONUT simplifies prediction of transplant outcomes

August 19, 2019 -

Int J Hematol

Adolescent hypomania, ADHD share genetic risk factors

August 16, 2019 -

JAMA Psychiatry

ACIP updates HPV vaccine recommendations for adults

August 16, 2019 -

MMWR Morb Mortal Wkly Rep

Virtual reality eases pain in hospitalized patients

August 16, 2019 -

PLoS ONE

Inpatient glycemic control: resident confidence exceeds knowledge

August 16, 2019 -

Endocr Pract

Statins are tied to reduced mortality in compensated liver disease

August 16, 2019 -

Sci Rep

CKD: risk for kidney failure is 50% higher in elderly men vs women

August 16, 2019 -

Am J Kidney Dis

Taselisib + letrozole combination active in ER+, HER2− early breast cancer

August 16, 2019 -

Lancet Oncol

August 16, 2019 -

JAMA Netw Open

ECG in the delivery room: fewer intubations but no mortality change

August 16, 2019 -

Resuscitation

Oropharynx SCC: TORS, radiotherapy yield similar QoL in randomized trial

August 16, 2019 -

Lancet Oncol

NSCLC: step counts can help evaluate fitness for chemoradiation

August 16, 2019 -

Int J Radiat Oncol Biol Phys

Ultrasound predicts constipation treatment response

August 16, 2019 -

JGH Open

Chronic-phase CML: frontline nilotinib delivers high-level response, adherence

August 16, 2019 -

Br J Haematol

Gallbladder cancer: adjuvant CRT extends survival in node-positive disease

August 16, 2019 -

Sci Rep

Surgery vs radiotherapy for high-grade prostate cancer with low PSA

August 16, 2019 -

Front Oncol

Melanoma: dual BRAF/MEK inhibition extends survival in meta-analysis

August 16, 2019 -

Cancer Med

PCOS: body image distress appears to mediate anxiety, depression

August 15, 2019 -

Fertil Steril

Air pollution, especially ozone, tied to emphysema

August 15, 2019 -

JAMA

DM care cascade hasn’t improved since 2005

August 15, 2019 -

JAMA Intern Med

AAN, AHS issue new guidelines for pediatric migraine

August 15, 2019 -

Neurology

For nontraumatic OHCA, prehospital critical care adds little

August 15, 2019

Early gluten intake tied to celiac risk among susceptible children

August 15, 2019 -

JAMA

FDA approves pretomanid for highly drug-resistant TB

August 15, 2019 -

US Food & Drug Administration

Bladder cancer: survival outcomes similar with robotic vs open cystectomy

August 15, 2019 -

J Clin Med

NSCLC: European consensus report defines oligometastatic disease

August 15, 2019 -

J Thorac Oncol

T2 melanoma: young age, LVI among predictors of SLN metastasis

August 15, 2019 -

Ann Surg Oncol

Hand grip strength predicts mortality risk in patients with cirrhosis

August 15, 2019 -

Hepatol Res

Vitamin D: meta-analysis suggests lipid benefit in certain patients

August 15, 2019 -

Nutr Rev

DAA triplet shows 96% efficacy in refractory HCV

August 15, 2019 -

J Hepatol

NHL: study identifies 2 risk factors for rituximab infusion reactions

August 15, 2019 -

Clin Lymphoma Myeloma Leuk

Breast cancer: T2DM tied to higher odds of TNBC vs ER+/HER2− tumors

August 15, 2019 -

Cancer Epidemiol Biomarkers Prev

HCC: NAFLD etiology tied to more surgical complications but better survival

August 15, 2019 -

J Am Coll Surg

Conference Coverage

Essential news from major medical conferences

ASM Microbe 2019

San Francisco, California, June 20 - 24

ADA 2019

San Francisco, California, June 7 - 11

More Conference Coverage

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

The patients were radioactive, but no one told paramedics or doctors

August 19, 2019

Curious about aerospace medicine?

August 19, 2019

Providers to leave Title X, reducing access to reproductive health care

August 19, 2019

Killer heat, shift to nighttime activities could affect clinical practice

August 19, 2019

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

When does a stroke hint at cancer?

Predictors of underlying neoplasm.

August 20, 2019

Treatment duration for UTIs in men

August 19, 2019

Physicians in pain

August 16, 2019