Recommended on Univadis

  • Clinical Essentials from Medicine (Baltimore)
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CCRT for cervical cancer: which regimen is best?

Network meta-analysis evaluates 12 concurrent chemotherapy regimens.

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  • Clinical Essentials from Eur J Prev Cardiol
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Multivessel disease predicts mortality in type 1 diabetes

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  • Clinical Essentials from MMWR Morb Mortal Wkly Rep
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Serologic-assessed immunity to polio in US children not recommended

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  • Clinical Essentials from Antimicrob Agents Chemother
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Selecting pneumonia antimicrobials: how does ceftazidime-avibactam measure up?

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  • Clinical Essentials from Aging Dis
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Low normal TSH linked to osteoporosis in older women

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  • Clinical Essentials from Annals of Internal Medicine
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Knee and hip osteoarthritis interventions no better than usual care

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  • Clinical Essentials from Arthritis Care Res (Hoboken)
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Rheumatoid arthritis: seropositive RA linked to earlier menopause

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  • Clinical Essentials from Ann Intern Med
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ACP, AAFP defy trends in latest hypertension guidelines

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  • Clinical Essentials from J. Clin. Oncol
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HCC: is sorafenib more effective in HCV+ patients?

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Professional Essentials

  • US Professional News

Doctors who tweet about drugs are likely to have financial ties

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  • US Professional News

Physicians in some specialties, regions charge much more than Medicare rates

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  • US Professional News

A third of physicians are offering telehealth, another third are not interested

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  • US Professional News

Family rudeness affects NICU care

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  • Patients Will Be Asking

Should I worry about my teething child's favorite chew toy?

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  • US Professional News

Gawande comes to defense of primary care in New Yorker essay

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New on Univadis

  • Clinical Essentials from Blood
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Lymphoma: is immune checkpoint therapy linked to immune adverse events after transplant?

Unusually virulent GVHD was observed in several patients.

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  • Clinical Essentials from Int J Clin Oncol
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Stage III colon cancer: preplanned safety analysis of 12-mo adjuvant capecitabine

Whether treatment reduces peak recurrence risk between 12 and 18 mo remains unclear.

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  • Clinical Essentials from JAMA Oncol
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Prostate cancer: PSA nadir >0.5 ng/mL after RT/ADT identifies high-risk for death

PSA nadir over 0.5 ng/mL could be used to select men for early entry into clinical trials prior to PSA recurrence.

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  • Clinical Essentials from Prostate Cancer Prostatic Dis
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Prostate cancer: does the new ISUP grouping system improve accuracy of risk prediction?

The new 5-tier grouping system predicted recurrence-free survival, but was it better than the current 3-tier grouping method?

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  • Clinical Essentials from Cochrane Database Syst Rev
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Tension headache: patients satisfied with aspirin, but not pain-free

Aspirin may be a good first-line treatment.

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  • Clinical Essentials from Lancet
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Intraventricular hemorrhage: no benefit from irrigation with alteplase

Preliminary data had suggested that alteplase was a safe method for removing intraventricular hemorrhages.

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  • Clinical Essentials from Pediatrics
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Neonatal abstinence syndrome: effects may persist into adolescence

Is NAS an intergenerational problem?

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  • Clinical Essentials from Clin Cancer Res
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CLL: single-agent ibrutinib 420 mg/d delivers durable, tolerable response

Results after more than 3 y of follow-up in previously untreated and relapsed/refractory patients.

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  • Clinical Essentials from World J Psychiatry
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In comorbid OCD and psychosis, CBT works

Evidence supporting the current recommendations is limited and controversial, and drug combinations can have adverse outcomes.

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Lipids and CAD Vitals for January 2017
  • Monthly Essentials
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Lipids and CAD Vitals for January 2017

More patients need high-dose statins | Statin treatments underused | Young adults with high LDL-C levels not taking statins

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  • Clinical Essentials from Nat Rev Rheumatol
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Osteoarthritis: leptin has many roles in rheumatic conditions

Understanding how leptin leptin works may lead to new options for inflammatory diseases.

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  • Clinical Essentials from Antivir Ther
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HIV: tenofovir alafenamide regimen yields low resistance rates

A single-tablet regimen that includes ECF with TAF may represent a durable HIV treatment option.

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  • Clinical Essentials from J Am Coll Cardiol
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More than 70% of elderly survive at least 2 y after secondary prevention ICD implantation

Although survival is high, two-thirds were hospitalized and 1 in 5 were admitted to a skilled nursing facility.

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  • Clinical Essentials from J Invasive Cardiol
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PCI: is there a selection bias against women with chronic total occlusion?

Even though procedural success and MACE rates were similar between sexes, only 14% of CTO-PCI patients were women.

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