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News

Today’s most essential news for your practice, in time-saving summaries.

CLL: 1L ibrutinib delivers superior PFS vs chemoimmunotherapy

Phase 3 trial of ibrutinib with/without rituximab vs bendamustine-rituximab in older patients.

December 11, 2018 -

N Engl J Med

Adjuvant T-DM1: a new standard for high-risk HER2+ breast cancer?

KATHERINE shows 50% lower recurrence vs trastuzumab in patients with residual disease.

December 11, 2018 -

N Engl J Med

CRC: postsurgical aspirin associated with survival benefit

Aspirin appeared to improve mortality, no matter when it was initiated.

December 11, 2018 -

J Gastroenterol Hepatol

SCLC: CRT yields better OS in stage I-II vs stage III disease

CONVERT secondary analysis finds once- and twice-daily RT similarly effective for early-stage SCLC.

December 11, 2018 -

JAMA Oncol

IBD tied to risk for prostate cancer

December 11, 2018 -

Eur Urol

Review ties childhood cancer RT to later thyroid malignancy

December 11, 2018 -

Eur J Epidemiol

Lipid therapy intensity and adherence: more is better for CVD risk

December 10, 2018 -

JAMA Netw Open

Pediatric epilepsy, febrile seizures raise neuropsychiatric risk

December 10, 2018 -

Lancet Child Adolesc Health

SLE linked to higher risk for 15 cancers in meta-analysis

December 10, 2018 -

Arthritis Res Ther

Glargine-300 bests glargine-100 in T1D and T2D

December 10, 2018 -

Acta Diabetol

Misoprostol alone is reasonable for MAB

December 10, 2018 -

Obstet Gynecol

Post-blunt-trauma bowel injury on CT: consider adhesion likelihood

December 10, 2018 -

Am J Surg

Cochrane on COPD: LAMA/LABA wins among options to reduce exacerbations

December 10, 2018 -

Cochrane Database Syst Rev

Opioid epidemic tied to infective endocarditis spike in NC

December 10, 2018 -

Ann Intern Med

CLL: front-line ibrutinib/obinutuzumab yields superior PFS in iLLUMINATE

December 10, 2018 -

Lancet Oncol.

Deadly brain-eating amoeba linked to nasal wash

December 10, 2018

Cochrane review: HFUS of uncertain benefit for skin cancer diagnosis

December 10, 2018 -

Cochrane Database Syst Rev

Opioid crisis: reducing opioid use after CD

December 10, 2018 -

Obstet Gynecol

HPV tied to cervical cancer risk regardless of cell abnormalities

December 10, 2018 -

Cancer

SABCS 2018 — Mastectomy, radiation associated with some reduced QoL measures

December 10, 2018

CRC: IV 5-FU tops capecitabine for response rate, safety

December 10, 2018 -

Curr Treat Options Oncol

NSCLC with brain mets: higher-dose afatinib yields better PFS

December 10, 2018 -

BMC Cancer

WHI: normal BMI with high body fat tied to breast cancer risk

December 10, 2018 -

JAMA Oncol

BCa: men have worse survival than women in early-stage disease

December 10, 2018 -

Am J Clin Oncol

Practice must pay $853K for releasing medical records

December 10, 2018

Data sharing helped wildfire victims get records

December 10, 2018

29% of U.S. physicians foreign-born

December 10, 2018

PCOS: higher LH, androgen, and insulin levels found in daughters

December 10, 2018 -

Fertil Steril

CD: infliximab to CT-P13 switch found safe in real-word study

December 10, 2018 -

Dig Dis Sci

PCI vs CABG for left main disease: 10-year outcomes are largely comparable

December 10, 2018 -

J Am Coll Cardiol

SABCS 2018 — Oxybutynin reduces hot-flash frequency and interference with QoL

December 10, 2018

SABCS 2018 — Lifestyle intervention improves weight loss after chemotherapy

December 10, 2018

Head/neck SCC: metformin fails to yield survival benefit in Canadian study

December 10, 2018 -

J Otolaryngol Head Neck Surg

Surveillance MRI shows very low yield after bilateral mastectomy, reconstruction in Israeli study

December 10, 2018 -

Breast Cancer Res Treat

Fluoxetine misses the mark as poststroke therapy

December 07, 2018 -

Lancet

Liraglutide's CV benefit confirmed in real-world data

December 07, 2018 -

Lancet Diabetes Endocrinol

Cochrane: "skin scrape" cytology can help confirm suspected BCC

December 07, 2018 -

Cochrane Database Syst Rev

Meta-analysis: best interventions for acute diarrhea, gastroenteritis in kids

December 07, 2018 -

PLoS One

Meta-analysis: educational, behavioral interventions improve gout outcomes

December 07, 2018 -

Ther Adv Musculoskelet Dis

Smoking cessation does not worsen symptoms of psychosis

December 07, 2018 -

Lancet Psychiatry

SABCS 2018 — Accelerated PBI, WBI not quite equal for ipsilateral tumor recurrence

December 07, 2018

SABCS 2018 — Low-dose tamoxifen reduces recurrence of breast EIN

December 07, 2018

MIBC: 2-month or more NACT delay tied to upstaging

December 07, 2018 -

Urol Oncol

About 1 in 3 autistic children in United States receives no treatment

December 07, 2018 -

JAMA Pediatr

Apple says smartwatch not for Afib patients

December 07, 2018

GDM exposure affects offspring into adolescence

December 07, 2018 -

J Clin Endocrinol Metab

FAAH inhibitor helps men quit pot, eases withdrawal

December 07, 2018 -

JAMA Psychiatry

Influenza, ILI: low and high BMI predict increased hospitalization risk

December 07, 2018 -

Influenza Other Respir Viruses

SABCS 2018 — Axillary RT, ALND yield similar outcomes in early breast cancer

December 07, 2018

KEYNOTE-028: pembrolizumab shows efficacy in ovarian cancer

December 07, 2018 -

Gynecol Oncol

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

Practice must pay $853K for releasing medical records

December 10, 2018

Deadly brain-eating amoeba linked to nasal wash

December 10, 2018

Data sharing helped wildfire victims get records

December 10, 2018

29% of U.S. physicians foreign-born

December 10, 2018

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

Lifetime risk for prostate cancer

What are the odds?

December 11, 2018

Diagnosis of supraspinatus rotator cuff tear

December 10, 2018

Which is the better option for NSCLC?

December 07, 2018