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News

Today’s most essential news for your practice, in time-saving summaries.

Trauma exposure in pediatrics: seriously consider posttraumatic depression

Depression is a common direct response to trauma in this patient population.

June 19, 2019 -

J Affect Disord

Osteoarthritis: fasinumab improves pain, function in phase 2b/3

Participants had a history of inadequate response or intolerance to analgesics.

June 19, 2019 -

Arthritis Rheumatol

Drivers of desired complete clearance in psoriasis, atopic dermatitis

A cross-sectional study of more than 7000 patients.

June 19, 2019 -

J Am Acad Dermatol

Hypertension guidelines in US and Europe: mind the gap

JACC comparison highlights key difference despite use of the same evidence base.

June 19, 2019 -

J Am Coll Cardiol

Elizabethkingia meningoseptica: multipronged antibiotics best for children

June 19, 2019 -

J Med Microbiol

Can we reduce perineal trauma during childbirth?

June 19, 2019 -

Eur J Obstet Gynecol Reprod Biol

PPI pendulum swings again: long-term PPI use linked to gastric cancer

June 19, 2019 -

J Gastroenterol Hepatol

Neurofilament light helps differentiate between clinically similar neurological conditions

June 19, 2019 -

JAMA Neurol

Apalutamide delays progression in metastatic, castration-sensitive prostate cancer

June 19, 2019 -

N Engl J Med

EHA 2019 – Scientific Working Group – Patient reported outcome measures in hematological malignancies: needs and news

June 19, 2019

EHA 2019 – Gilteritinib, a new treatment paradigm for relapsed/refractory acute myeloid leukaemia

June 19, 2019

EHA 2019 – Nelarabine in the real-world, an effective option for relapsed/refractory T-acute lymphoblastic leukaemia/lymphoma

June 19, 2019

EHA 2019 – Acalabrutinib shows remarkable benefit in relapsed or refractory chronic lymphocytic leukaemia

June 19, 2019

EHA 2019 – Isatuximab improves progression-free survival in patients with relapsed/refractory multiple myeloma

June 19, 2019

More than half a million opioid abusers have children at home

June 19, 2019 -

Ann Fam Med

ICDs fail to prevent sudden cardiac death in dialysis patients

June 19, 2019 -

Circulation

Lipid-lowering medications are linked to reduced retinopathy risk in T2D

June 19, 2019 -

Am J Ophthalmol

Royal College of Obstetricians and Gynecologists guidelines: PPROM after 24 weeks

June 19, 2019 -

BJOG

HCV: SOF/VEL yields 95% clearance rate in dialysis patients

June 19, 2019 -

J Hepatol

Metastatic TNBC: phase 2 points to benefit with niraparib + pembrolizumab

June 19, 2019 -

JAMA Oncol

FDA approves trastuzumab biosimilar for breast, gastric cancers

June 19, 2019

Relapsed multiple myeloma: cardiotoxicity risk factors with carfilzomib

June 19, 2019 -

J Clin Oncol

Coagulation parameters predict polycystic ovary syndrome

June 19, 2019 -

Eur J Obstet Gynecol Reprod Biol

Overdose patients: when is a brain scan indicated?

June 19, 2019 -

Emerg Med Australas

Oral cancer: 4 prognostic factors in node-negative disease

June 19, 2019 -

Oral Oncol

HCC: radiofrequency ablation effective for single 3-4-cm tumors

June 19, 2019 -

J Gastrointest Surg

Suicide rate among adolescents, young adults highest since 2000

June 18, 2019 -

JAMA

Sperm fragmentation threshold for infertility might be far below current cutoff

June 18, 2019 -

Int J Environ Res Public Health

FDA approves pediatric T2D indication for liraglutide

June 18, 2019 -

FDA

Osteoporosis: long-term denosumab cuts risk for upper limb fracture

June 18, 2019 -

Osteoporos Int

Metagenomic test improves diagnosis in meningitis, encephalitis

June 18, 2019 -

N Engl J Med

High CAC score in middle age heralds LV remodeling

June 18, 2019 -

Circ Cardiovasc Imaging

Flesh-eating bacteria in new areas: is climate change to blame?

June 18, 2019 -

Ann Intern Med

Lung cancer detection: artificial intelligence model bests radiologists

June 18, 2019 -

Nat Med

ADA 2019—After 50 years of waiting: linagliptin and glimepiride do not differ in CVD outcomes

June 18, 2019

EHA 2019 – The addition of daratumumab results in a robust clinical benefit in transplant-eligible newly diagnosed multiple myeloma patients

June 18, 2019

EHA 2019 – Induction with obinutuzumab plus DHAP in mantle cell lymphoma leads to a high level of minimal residual disease negativity

June 18, 2019

EHA 2019 – Complex karyotype influences the response to therapy in treatment-naïve CLL patients with coexisting conditions

June 18, 2019

EHA 2019 – Durable benefits with brentuximab vedotin plus chemotherapy as frontline treatment in classical Hodgkin lymphoma

June 18, 2019

EHA 2019 – Outcomes after different intensity of conditioning in acute myeloid leukaemia: the importance of genomic variants

June 18, 2019

Inpatient opioids tied to doubled risk for at-home use

June 18, 2019 -

Ann Intern Med

Brain injury: what factors influence decisions to withdraw life support?

June 18, 2019 -

CMAJ

Adolescent sexting is linked to a host of unhealthy behaviors

June 18, 2019 -

JAMA Pediatr

Diabetic CKD: no link between metformin, acidosis after contrast CT

June 18, 2019 -

Clin Radiol

Kidney disease: add-on evolocumab lowers cardiovascular risk

June 18, 2019 -

J Am Coll Cardiol

Providing ob-gyn care for transgender men, gender-nonbinary patients: a review

June 18, 2019 -

Obstet Gynecol

CML-CP: can TKI deescalation foster improved treatment-free remission?

June 18, 2019 -

Lancet Haematol

Breast cancer: meta-analysis identifies best target volume for regional node irradiation

June 18, 2019 -

Radiat Oncol

ADA 2019—Linagliptin is comparable to placebo for CV/renal risks: CARMELINA

June 18, 2019

Hidradenitis suppurativa tied to excess mortality risk

June 18, 2019 -

J Am Acad Dermatol

Conference Coverage

Essential news from major medical conferences

ADA 2019

San Francisco, California, June 7 - 11

June 11, 2019

ASCO 2019

Chicago, Illinois, May 31 - June 4

June 04, 2019

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

Insulin rationing extremely common among US patients with T1D

June 19, 2019

Medical aid-in-dying legal in Maine

June 19, 2019

Robocalls tying up hospital phone lines

June 19, 2019

Hospital sued after allegations of inadequately sterilized equipment

June 19, 2019

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

Image Quiz: Chest pains from an unusual cardiac source

A 61-year-old woman presents with complaints of palpitations and dyspnea on exertion. What does the imaging show?

June 20, 2019

Recommended epilepsy treatment options

June 19, 2019

Who is really at risk for Alzheimer’s?

June 18, 2019