Recommended on Univadis

  • Clinical Essentials from Growth Factors
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Gastric cancer: trastuzumab improves outcomes in meta-analysis

Adding trastuzumab to chemotherapy significantly improved ORR, PFS, and OS.

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  • Clinical Essentials from World Health Organization
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WHO prequalifies its first HCV rapid test

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  • Clinical Essentials from Arthritis Res Ther
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Rheumatoid arthritis: biologics linked to lower heart disease risk

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  • Clinical Essentials from JAMA Cardiol
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Muscular dystrophy: ACE inhibitor slows myocardial fibrosis progression

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  • Clinical Essentials from U.S. Department of Health and Human Services.
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E-cigarettes “a public health concern”: Surgeon General’s report

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  • Clinical Essentials from Pediatr Diabetes
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Link between tight glycemic control and severe hypoglycemia in type 1 diabetes may be fading

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  • Clinical Essentials from Intern Emerg Med
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Critique of Afib guidelines shows considerable variation in ER management recommendations

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  • Clinical Essentials from Eur Urol
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Clear-cell RCC: 43% of metastatic tumors differ from primary subtype

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  • Clinical Essentials from JAMA Psychiatry
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Childhood depression: what precedes it?

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Professional Essentials

  • US Professional News

Depression is a common problem for medical students, new research suggests

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  • US Professional News

Hospitals and physician groups frequently demand payment from patients up front

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  • US Professional News

ACA repeal could raise number of insured by 30 million people, report suggests

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  • US Professional News

Patients who choose doctors with lower-priced office visits save hundreds per year, study suggests

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  • Patients Will Be Asking

Should I try harder to be optimistic?

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  • Patients Will Be Asking

Are my kid’s headphones too loud?

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New on Univadis

  • Clinical Essentials from Leuk Lymphoma
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Pediatric HL: could ABVD replace current regimens?

Findings from the largest study so far of ABVD in pediatric HL.

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  • Clinical Essentials from BJU Int
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Prostate cancer: only a minority of patients with relapsing disease benefit from AC PET

False-positives indicate that factors other than tumor metabolism induce increased 11C-acetate uptake.

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Epinephrine stocking programs in public food areas are hampered by liability concerns │WAO
  • Conference Essentials
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Epinephrine stocking programs in public food areas are hampered by liability concerns │WAO

The scope of accidental exposure in food-allergic individuals dining out is unknown

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  • Clinical Essentials from Arthritis Res Ther
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Rheumatoid arthritis: abatacept and tocilizumab are similarly effective after anti-TNF discontinuation

Head-to-head comparisons are needed for RA treatment options.

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  • Clinical Essentials from Ann Allergy Asthma Immunol
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Mepolizumab for asthma: is it cost-effective?

Study shows 89% discount needed to reach cost-efficacy threshold

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  • Clinical Essentials from J Orthop Surg Res
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TKA: double nerve block tops FNB + LIA for post-op pain

A meta-analysis of randomized controlled trials.

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  • Clinical Essentials from Clin Gastroenterol Hepatol
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Ulcerative colitis: how should patients with low-grade dysplasia be managed?

Results of an outcomes meta-analysis.

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  • Clinical Essentials from J Matern Fetal Neonatal Med
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CF in pregnancy: more maternal comorbities, adverse perinatal effects

Women with cystic fibrosis are more likely to have gestational diabetes, fetal anomalies, and preterm delivery.

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  • Clinical Essentials from Obstet Gynecol
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Sleep problems in pregnancy tied to complications

Sleep-disordered breathing is a modifiable risk factor for pregnancy complications.

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  • Clinical Essentials from Circulation
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Ambulatory BP isn’t lower than clinic-based BP in younger healthy patients

Some with normal clinic measures have masked hypertension.

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  • Clinical Essentials from J Am Heart Assoc
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Small systolic BP increases are associated with greater mortality in African Americans

Association with HF hospitalization risk also identified.

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HPV associated oropharyngeal cancers: women and nonwhites not spared
  • JAMA Oncology
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HPV associated oropharyngeal cancers: women and nonwhites not spared

The proportion of oropharyngeal cancer caused by HPV has increased significantly among all sex and race groups from 1995 to 2012

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Pneumonia: Monthly Essentials December 2016
  • Monthly Essentials
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Pneumonia: Monthly Essentials December 2016

Oral care to prevent ventilator-associated pneumonia | Oral antibiotics for complicated pneumonia | Benzos and zopiclone linked to pneumonia

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  • Clinical Essentials from World J Gastroenterol
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HBV-related HCC: post-LT survival lower in patients with diabetes

Presence of diabetes independently predicts poor survival, but not recurrence.

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