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News

Today’s most essential news for your practice, in time-saving summaries.

aRCC: front-line avelumab-axitinib tops sunitinib in JAVELIN Renal 101

Benefit observed regardless of risk group or PD-L1-positive status.

February 22, 2019 -

N Engl J Med

Methotrexate is meh for secondary prevention in atherosclerotic disease

Low dose of drug also tied to unexpected increase in skin cancer.

February 22, 2019 -

N Engl J Med

IBD outcomes vary with type after Roux-en-Y vs sleeve gastrectomy

Patients with CD experience greater increase in med requirements after RYGB.

February 22, 2019 -

J Am Coll Surg

Shoulder replacement failure is more common in younger men

Adverse event rates are higher than previously reported.

February 22, 2019 -

BMJ

NSAID exposure tied to AKI, CKD in active younger adults

February 22, 2019 -

JAMA Netw Open

SGLT2is top GLP-1RAs for some patients with T2D

February 22, 2019 -

Circulation

Timing of IOL: 41 weeks vs 42 weeks

February 22, 2019 -

BMJ

HIV: CVD, renal disease top factors for poorer survival in elderly

February 22, 2019 -

BMJ Open

FDA adds boxed warning for gout med febuxostat

February 22, 2019 -

FDA

eBCa: should anthracyclines precede taxanes? A Cochrane review

February 22, 2019 -

Cochrane Database Syst Rev

HNC: low yield for >2-year surveillance after definitive RT

February 22, 2019 -

Cancer

RA: unaffected siblings have increased ACS risk

February 22, 2019 -

Ann Rheum Dis

Staging aortic stenosis: echo-based system is prognostic after TAVR

February 22, 2019 -

JAMA Cardiol

Headache, back pain in ED: which serious diagnoses are missed?

February 22, 2019 -

Ann Emerg Med

Right-sided CRC tied to poorer survival only in stage IV disease

February 22, 2019 -

Front Oncol

PTMC: high-risk features revealed by surgery in 28% of patients

February 22, 2019 -

Front Endocrinol (Lausanne)

Lung cancer: high-dose steroids, CCRT tied to higher PJP risk

February 22, 2019 -

Sci Rep

CLL: ibrutinib yields favorable outcomes across treatment lines

February 22, 2019 -

Am J Hematol

Colorectal polyps: mixed-modality training improves PIVI performance

February 22, 2019 -

Clin Gastroenterol Hepatol

Gastric cancer: high TIL levels show prognostic value

February 22, 2019 -

Front Immunol

Kidney injury seen in an “alarming” number of PPI users

February 21, 2019 -

Sci Rep

OSA treatment with positive airway pressure: AASM updates guideline

February 21, 2019 -

J Clin Sleep Med

Advanced RCC: pembrolizumab-axitinib tops sunitinib in KEYNOTE-426

February 21, 2019 -

N Engl J Med

VUR: long-term low-dose prophylaxis does little

February 21, 2019 -

Cochrane Database Syst Rev

CDC: homelessness now an indication for HepA vaccination

February 21, 2019 -

MMWR Morb Mortal Wkly Rep

Schizophrenia: adjunctive antidepressants may top antipsychotic switch

February 21, 2019 -

JAMA Psychiatry

Opioid abuse, dependence tied to tranquilizer misuse

February 21, 2019 -

Drug Alochol Depend

HF boosts mortality risk for surgical patients, regardless of symptoms or EF

February 21, 2019 -

JAMA

PCa: NRG trial supports hypofractionated RT as standard of care

February 21, 2019 -

JAMA Oncol

Glyphosate exposure ups NHL risk by 41% in meta-analysis

February 21, 2019 -

Mutat Res

BCa: online CBT helps reduce treatment-induced menopausal symptoms

February 21, 2019 -

J Clin Oncol

Stage I NSCLC: SABR tops standard RT in phase 3 CHISEL trial

February 21, 2019 -

Lancet Oncol

Nut intake is tied to reduced CVD death in DM

February 21, 2019 -

Circ Res

Achilles tendon rupture: what's the best treatment to avoid complications?

February 21, 2019 -

Am J Sports Med

Compressed influenza vaccination: a good idea for older adults?

February 21, 2019 -

Am J Prev Med

Alpha-1 blockers are linked to better resolution of UR/BPO

February 21, 2019 -

Eur Urol

Pregnancy: low cortisol/cortisone ratio predicts preeclampsia

February 21, 2019 -

J Clin Endocrinol Metab

Cochrane: little data on penicillin efficacy in newborns with congenital syphilis

February 21, 2019 -

Cochrane Database Syst Rev

Croup: which ED patients can go home?

February 21, 2019 -

J Paediatr Child Health

NSCLC: high NLR tied to poorer PFS, OS with PD-1/PD-L1 inhibitors

February 21, 2019 -

Lung Cancer

Dementia incidence highly variable after stroke/TIA

February 20, 2019 -

Lancet Neurol

Monthly buprenorphine injection effective for opioid use disorder

February 20, 2019 -

Lancet

Infectious diarrhea: pocket synopsis for diagnosis and management

February 20, 2019 -

JAMA

USHER: HCV+ heart transplant safe for HCV-negative patients

February 20, 2019 -

Am J Transplant

How many DM patients are buying OTC insulin?

February 20, 2019 -

JAMA Intern Med

Preconception smoking is associated with birth defects

February 20, 2019 -

Am J Obstet Gynecol

During RSI, bag-mask ventilation before laryngoscopy improves oxygenation: PreVent

February 20, 2019 -

N Engl J Med

Cervical cancer: scaled-up HPV vaccine, screening could prevent 13 million cases by 2069

February 20, 2019 -

Lancet Oncol

CRPC: add-on darolutamide ups metastasis-free survival in ARAMIS

February 20, 2019 -

N Engl J Med

ICU: nurse-led intervention fails to lower PTSD symptoms in POPPI

February 20, 2019 -

JAMA

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

FDA chief suggests federal action on state vaccine exemptions

February 21, 2019

Physician encourages young women to go into surgery

February 21, 2019

Dallas physicians dispute alleged kickbacks for surgeries

February 20, 2019

Kaiser Permanente's new medical school to be tuition-free for early students

February 20, 2019

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

New cardiac imaging guidelines

Multisociety appropriate use criteria.

February 22, 2019

Image Quiz: 32-year-old with eyelid pain and swelling

February 21, 2019

Recognizing palmoplantar psoriasis

February 20, 2019