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News

Today’s most essential news for your practice, in time-saving summaries.

Trastuzumab-r ABC: add-on pembrolizumab does well in PANACEA

Adding pembrolizumab to trastuzumab yields 15% ORR in PD-L1+ patients.

February 18, 2019 -

Lancet Oncol

Breast cancer: advances avert a half-million deaths over 30 years

Preventive screening and treatment advances have contributed to saving lives.

February 18, 2019 -

Cancer

CRC: synchronous liver resection tied to more complications

Findings suggest a role for patient selection.

February 18, 2019 -

J Surg Res

Hypopharyngeal cancer: high NLR predicts poor CRT outcomes in Taiwanese study

Data show poor response and survival.

February 18, 2019 -

Sci Rep

Low-risk DTC: discharge to primary care after 5 years is safe, says British study

February 18, 2019 -

Clin Oncol (R Coll Radiol)

eBCa: SSO-ASTRO margins guideline cuts BCS reoperation rate

February 18, 2019 -

Am J Surg

Stroke: ABCB1 polymorphism reduces benefit of adding clopidogrel to aspirin

February 15, 2019 -

JAMA Neurol

Antipsychotic medication use tied to mortality risk among elders

February 15, 2019 -

J Gerontol A Biol Sci Med Sci

PCOS: meta-analysis finds exercise beneficial

February 15, 2019 -

Syst Rev

Psoriasis: AAD-NPF guidelines focus on comorbidities

February 15, 2019 -

J Am Acad Dermatol

Poor statin adherence leads to increased mortality risk in ASCVD

February 15, 2019 -

JAMA Cardiol

More enterovirus infections in early childhood bumps celiac disease risk

February 15, 2019 -

BMJ

Morphine use declines post-THA with NSAID +/− acetaminophen

February 15, 2019 -

JAMA

CDC: influenza vaccine efficacy at 47% in adults, 61% in kids

February 15, 2019 -

MMWR Morb Mortal Wkly Rep

Low-risk PCa: active surveillance triples during 2010-2015

February 15, 2019 -

JAMA

Pelvic floor disorders: does mode of delivery matter?

February 15, 2019 -

Journal of Obstetrics and amp; Gynecology and Reproductive Biology

Detecting dysplasia in IBD: chromoendoscopy is better than white light endoscopy

February 15, 2019 -

J Dig Dis

FDA approves triclabendazole for fascioliasis

February 15, 2019 -

FDA

EFSUMB: guidelines for endorectal, endoanal, and perineal ultrasound

February 15, 2019 -

Ultrasound Int Open

In women without obstructive CAD, coronary reactivity predicts adverse outcomes: WISE

February 15, 2019 -

J Am Coll Cardiol

ARDS: modified lung recruitment maneuvers improve outcomes

February 15, 2019 -

J Clin Med

Bronchiolitis: bedside ultrasound in ED predicts need for respiratory support

February 15, 2019 -

Eur J Pediatr

HBV: comorbid DM tied to higher odds of HCC, death

February 15, 2019 -

J Viral Hepat

R/R ATL: mogamulizumab benefit confirmed, even in the elderly

February 15, 2019 -

Eur J Haematol

cT2-cT3 rectal cancer: is RT boost better than oxaliplatin?

February 15, 2019 -

Radiother Oncol

NSCLC: ECOG status predicts ICI outcomes in elderly patients

February 15, 2019 -

J Am Geriatr Soc

HPV+ OPSCC: deescalated RT noninferior to standard dose for survival

February 15, 2019 -

Radiother Oncol

Dietary interventions for IBD: Cochrane review finds only ambiguity

February 14, 2019 -

Cochrane Database Syst Rev

Young women at high CVD risk: the postpartum window is an opportunity

February 14, 2019 -

CMAJ

Jaw osteonecrosis is quite rare with denosumab treatment

February 14, 2019 -

J Clin Endocrinol Metab

Carotid stenosis: long-term outcomes favor endarterectomy over stenting

February 14, 2019 -

Lancet Neurol

Anorexia: olanzapine yields modest weight gain in randomized trial

February 14, 2019 -

Am J Psychiatry

In first-trimester miscarriage, expectant management is least effective

February 14, 2019 -

Hum Reprod Update

Noninvasive ventilation for COPD exacerbation: mortality is similar on wards vs ICU

February 14, 2019 -

Crit Care Med

Quadrivalent IIV reduces severe outcomes in children aged 6-35 months

February 14, 2019 -

Vaccine

MRSA tied to higher readmission rate, mortality than MSSA

February 14, 2019 -

Clin Infect Dis

Mediterranean diet tied to lower risk for bladder cancer

February 14, 2019 -

Eur J Nutr

Delaying colonoscopy after positive FIT could be costly

February 14, 2019 -

Dig Liver Dis

Merkel cell carcinoma: pembrolizumab boosts survival, tumor control

February 14, 2019 -

J Clin Oncol

HCV-1/4: 3D, 2D highly effective in pooled real-world studies

February 14, 2019 -

J Viral Hepat

T2D: achievement of ABC goals varies by season

February 14, 2019 -

Diabetes Care

Rotating night shift work affects age at menopause

February 14, 2019 -

Hum Reprod

Thrombectomy also benefits transferred late-window patients with ischemic stroke

February 14, 2019 -

JAMA Neurol

Meta-analysis: letrozole, LOD equally effective in clomiphene-resistant PCOS

February 14, 2019 -

Reprod Biol Endocrinol

Psoriasis: which risk factors predict discontinuation of biologic therapy?

February 14, 2019 -

Br J Dermatol

Migraine: MAST study identifies allodynia risk factors

February 14, 2019 -

Cephalalgia

Asymptomatic SIHD: revascularization offers possible benefit

February 14, 2019 -

JACC Cardiovasc Interv

R/R cHL: nivolumab yields favorable outcomes in pooled analysis

February 14, 2019 -

Clin Transl Oncol

Recurrence common in LA-NSCLC after trimodality therapy

February 14, 2019 -

Surg Today

Low adiponectin tied to breast cancer risk in Asians, not whites

February 14, 2019 -

Medicine (Baltimore)

Professional News

Essential news on the business and practice of medicine, in time-saving summaries.

Medicare pilot program diverts ambulances from ED

February 15, 2019

Oops—traders boost shares of wrong "Auris"

February 15, 2019

Many PCPs not ready to talk about cancer options

February 15, 2019

White House official's wife critical of vaccines

February 15, 2019

More Professional News

Quiz

1-minute quiz: Test your knowledge with today’s question.

Treatment guideline: infantile hemangiomas

When do IHs grow fastest?

February 19, 2019

Cheers to that: alcohol use in HF

February 18, 2019

Let the bacteria decide

February 15, 2019