Recommended on Univadis

  • Clinical Essentials from Lancet
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GLE/PIB yields 99% clearance rate in HCV with compensated cirrhosis

Data from the phase 3 Expedition-1 trial.

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  • Clinical Essentials from J Clin Oncol
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Breast cancer: 70-gene test changes 51% of chemo decisions

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  • Clinical Essentials from J Pain Res
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Caffeine with opioids effective in fibromyalgia

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  • Clinical Essentials from N Engl J Med
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ROOBY-FS trial: off-pump CABG raises 5-y mortality risk

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  • Clinical Essentials from PLoS One
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Fasting blood glucose test may miss diabetes diagnosis

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  • Clinical Essentials from Pediatrics
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AAP issues new guidelines for pediatric hypertension

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  • Clinical Essentials from J. Viral Hepat
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HCV-1b with cirrhosis: extending LDV/SOF duration tops adding RBV

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  • Clinical Essentials from Am. J. Obstet. Gynecol
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Society for Maternal-Fetal Medicine issues HCV guidelines

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  • Clinical Essentials from FDA
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FDA approves olaparib maintenance therapy for ovarian cancer

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Professional Essentials

  • Patients Will Be Asking

Will walnuts help me lose weight?

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  • US Professional News
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Questions about drug fast-tracking

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  • US Professional News

Physician moms work fewer hours

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  • US Professional News
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States getting creative for rural care

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  • US Professional News
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Racism in ED, says Oregon physician

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  • US Professional News
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Aid-in-dying drugs harder to come by

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New on Univadis

  • Clinical Essentials from Leukemia
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CML: patient, disease factors outweigh first-line treatment type

Non-CML factors have more influence on survival than first-line treatment selection.

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  • Clinical Essentials from Eur J Cancer
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Breast cancer brain mets: capecitabine adds survival benefit to lapatinib

Meta-analysis suggests combination therapy should be considered a first-line option.

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  • Clinical Essentials from J Clin Oncol
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Extensive stage SCLC: palifosfamide fails phase 3 MATISSE trial

Adding palifosfamide to carboplatin and etoposide failed to improve survival.

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Women’s Health Vitals for August 2017
  • Vitals
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Women’s Health Vitals for August 2017

Early term birth and pediatric T2D | First trimester vigorous physical activity.

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  • Clinical Essentials from Cancer
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Breast cancer: annual mammograms from age 40 save the most lives

CISNET modeling compares 3 widely debated approaches.

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  • Clinical Essentials from MMWR Morb Mortal Wkly Rep
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Counseling recommended for mixed HIV status couples planning conception

HIV+ men should be aware of the need for virologic suppression.

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  • Clinical Essentials from Paediatr Perinat Epidemiol
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Hypertension during pregnancy is associated with CVD later in life

Obstetrical history is an important part of a woman's health record.

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  • Clinical Essentials from Endocr Pract
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What’s the best treatment intensification strategy in type 2 diabetes?

Not all patients achieve recommended HbA1c levels even after adequate basal insulin titration.

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  • Clinical Essentials from PLoS One
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COPD and the link with diabetes

Increased inflammatory mediators in COPD or use of steroid therapy may increase new-onset diabetes risk.

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  • Clinical Essentials from Tech Coloproctol
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Rectal cancer: 5-y survival similar with laparoscopy, open surgery

A ,eta-analysis of randomized controlled trials.

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  • Clinical Essentials from JAMA Otolaryngol Head Neck Surg
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Obstructive sleep apnea: coagulation measures vary by severity

A retrospective cohort study assessing impact of OSA severity on hypercoagulability.

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  • Clinical Essentials from J Am Med Dir Assoc
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Nutrient interventions for Alzheimer’s disease lack strong evidence of benefit

A network meta-analysis of nutrients for treatment of Alzheimer’s disease.

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  • Clinical Essentials from J Neurol
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Use of epilepsy surgery varies by sociodemographic factors

A large national cohort study looks at the characteristics of patients undergoing epilepsy surgery.

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  • Clinical Essentials from Aliment Pharmacol Ther
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Exclusive enteral nutrition vs steroids for remission induction in pediatric Crohn’s

Intriguing meta-analysis results for a rarely used option.

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