Recommended on Univadis

  • Clinical Essentials from J Urol
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Enzalutamide benefits patients with mCRPC with low PSA levels

Post hoc analysis of PREVAIL study.

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  • Clinical Essentials from Cancer
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5 HNC quality metrics suitable for national adoption

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  • Clinical Essentials from Lancet Haematol
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CML: TKI dose de-escalation in patients with stable MMR or better

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  • Clinical Essentials from Lancet
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Ataluren benefits some boys with nonsense mutation Duchenne muscular dystrophy

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  • Clinical Essentials from Lancet
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HIV: LATTE-2 trial demonstrates efficacy of injectable, long-acting cabotegravir/rilpivirine

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  • Clinical Essentials from J Headache Pain
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Chronic migraine: A simpler protocol for Onabotulinumtoxin A injection treatment

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  • Clinical Essentials from Lancet HIV
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On-demand PrEP efficacious, safe for individuals at high risk for HIV

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  • Clinical Essentials from Can J Psychiatry
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New guidelines on managing young people at high risk of psychosis

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  • Clinical Essentials from Oncotarget
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Smoking and heroin dependence: a recipe for pain

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Professional Essentials

  • US Professional News
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Demand for primary care physicians is increasing their pay

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  • US Professional News
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New standardized form eases patient record requests

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  • US Professional News
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Former USC medical dean in drug scandal

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  • US Professional News
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Time to understand ACI

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  • US Professional News
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Number of physicians up 12%

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  • US Professional News
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Industry payments affect patient perception

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New on Univadis

  • Clinical Essentials from Br J Cancer
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Number of colorectal liver metastases shouldn’t preclude surgery

Patients with 10 or more CLM who underwent resection and chemotherapy had 52% OS at 3 y.

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  • Clinical Essentials from J Clin Oncol
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HER2+ breast cancer: 2 common trastuzumab-based chemotherapy regimens have similar efficacy, safety in older women

First head-to-head comparison of ACTH vs TCH.

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  • Clinical Essentials from JAMA Oncol
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Proton beam radiotherapy safe for unresectable NSCLC

PBT+adjuvant chemotherapy yielded 29% OS at 5 y in patients with advanced unresectable NSCLC.

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Respiratory Infection Vitals for July 2017
  • Vitals
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Respiratory Infection Vitals for July 2017

Reductions with inclusion of atypical pathogens in empiric treatment | PCV13 triggers adequate response long term in older adults.

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Ten-year outcomes good after ACL Reconstruction | AOSSM
  • Conference Essentials
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Ten-year outcomes good after ACL Reconstruction | AOSSM

Both IKDC and KOOS significantly improved after 2 y and were maintained at 6 and 10 y.

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Hematology-Oncology Vitals for July 2017
  • Vitals
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Hematology-Oncology Vitals for July 2017

Ibrutinib shows survival advantage over ofatumumab in relapsed CLL | 1 or 2 TKIs better than 3 before allogeneic HSCT in CML.

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  • Clinical Essentials from Int J Radiat Oncol Biol Phys
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Cervical cancer: shorter CRT interval improves OS

Timing and duration of CRT important in adjuvant setting.

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  • Clinical Essentials from Oncotarget
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Metastatic triple-negative breast cancer: add-on bevacizumab is the best of 8 targeted agents

Results of a network meta-analysis.

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  • Clinical Essentials from JAMA Dermatol
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Thin melanoma: patient age predicts LN positivity

Understanding factors associated with LN metastasis will help guide eligibility for sentinel LN biopsy.

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Nearly all athletes return to play following foot fracture fixation | AOSSM
  • Conference Essentials
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Nearly all athletes return to play following foot fracture fixation | AOSSM

Athletes are predisposed to foot fractures because of large stresses placed on the lower extremities.

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  • Clinical Essentials from Open Forum Infect Dis
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Community-acquired pneumonia: why do some patients get nonrecommended antibiotics?

Current guidelines recommend narrower spectrum antibiotics as first-line.

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  • Clinical Essentials from J Gen Intern Med
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Do you know all 11 risk factors for prediabetes?

Only 6% of primary care providers surveyed correctly identified them all.

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  • Clinical Essentials from Clin J Pain
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Endometriosis and chronic pelvic pain is associated with low poor health-related QoL

Treatment improves health-related QoL.

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  • Clinical Essentials from Diabetes Care
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What’s the best imaging technique for detecting diabetic foot osteomyelitis?

The various modalities have similar sensitivity, but specificity is higher with two.

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