Recommended on Univadis

  • Clinical Essentials from J Clin Oncol
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Renal cancer: cabozantinib tops sunitinib as first-line treatment

Preliminary data show a 20% decrease in the rate of death with cabozantinib compared with sunitinib.

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  • Clinical Essentials from N Engl J Med
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Physician opioid prescribing habits linked to risk for long-term patient use

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  • Clinical Essentials from BMJ
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Prevention of acute respiratory infections: “a major new indication for vitamin D supplementation”

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  • Clinical Essentials from BMC Surg
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Hepatectomy effective for managing gastric cancer liver metastases

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  • Clinical Essentials from Gastroenterology
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HCV: 6-trial analysis confirms EBR/GZR efficacy in compensated cirrhosis

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  • Vitals
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Skin Cancer Vitals for February 2017

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  • Clinical Essentials from Head Neck Surg
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Upper airway stimulation may improve several outcomes in OSA

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  • Clinical Essentials from BMC Geriatr
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Patients with dementia less likely to receive opioid analgesics after hip/pelvic fracture

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  • Clinical Essentials from Respir Med
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COPD: aclidinium/formoterol safety, efficacy confirmed at 52 wks

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Professional Essentials

  • US Professional News

Bundled payment models delayed, but not in immediate danger, HHS says

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  • US Professional News

Caribbean medical schools seek better image

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  • US Professional News

Kennedy says he expects Trump vaccine panel will move forward

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  • US Professional News

Court strikes down Florida law barring physicians from discussing firearms

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  • Patients Will Be Asking

What would the proposed replacement for Obamacare mean for me?

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  • US Professional News

Mandatory PDMP use related to safer opioid prescribing

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  • Clinical Essentials from Transl Pediatr
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HIV: fetal/neonatal NRTI exposure linked to developmental delay, behavioral disorders

ART is commonly used to reduce maternal HIV transmission.

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Asthma and COPD Vitals for February 2017
  • Vitals
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Asthma and COPD Vitals for February 2017

New COPD guidelines | Stepping down inhaled corticosteroids | Rotacaps/Rotahaler vs Diskus.

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Point-of-care early infant diagnosis enables earlier and increased ART initiation | CROI
  • Conference Essentials
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Point-of-care early infant diagnosis enables earlier and increased ART initiation | CROI

Novel point-of-care assays may increase access to EID and positively affect clinical care.

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  • Clinical Essentials from New England Journal of Medicine
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Baricitinib more effective than adalimumab or placebo in methotrexate-resistant RA

Favorable phase 3 results from the RA-BEAM trial of this oral Janus kinase inhibitor.

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Specific ART regimens used in pregnancy may affect adverse birth outcomes | CROI
  • Conference Essentials
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Specific ART regimens used in pregnancy may affect adverse birth outcomes | CROI

Among infants exposed to ART from conception, TDF/FTC/EFV was associated with the fewest adverse birth outcomes.

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  • Clinical Essentials from Clin Cancer Res
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MRCC: sunitinib-related cardiotoxicity is largely reversible

Is routine monitoring needed for asymptomatic patients?

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The EuSCAPE study to predict the occurrence of Klebsiella pneumoniae and E coli
  • The Lancet Infectious Diseases
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The EuSCAPE study to predict the occurrence of Klebsiella pneumoniae and E coli

A prospective, multinational surveillance of carbapenemase-producing Enterobacteriaceae

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  • Clinical Essentials from JAMA Dermatol
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Incorporating "ugly duckling sign" may improve melanoma diagnosis

Study evaluates the impact of including the sign in IPCA of nevi.

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  • Clinical Essentials from Clin Ther
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Gefinitib-resistant NSCLC: chemotherapy boosts survival

Chemotherapy improves survival after acquired gefitinib resistance, especially with continued gefitinib.

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  • Clinical Essentials from Otolaryngol Head Neck Surg
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Oropharyngeal SCC: Notch1 overespression linked to better survival

Prognostic value is independent of HPV status.

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  • Clinical Essentials from Cancer
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PTC: how does invasiveness affect clinicopathology?

NIFTP is a new classification meant to limit overtreatment of noninvasive disease.

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  • Clinical Essentials from Stroke
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Sepsis associated with increased stroke risk up to 365 d postadmission

Patients with sepsis remain at risk for stroke for up to a year after admission.

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  • Clinical Essentials from Dement Geriatr Cogn Disord.
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Strengths and weaknesses of the MoCA for frontotemporal dementias

Researchers found it out-performed standard assessments in some areas, but was lacking in others.

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Ultrasound distinguishes inflammatory from non-inflammatory disease in patients with abdominal pain and diarrhea | ECCO
  • Conference Essentials
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Ultrasound distinguishes inflammatory from non-inflammatory disease in patients with abdominal pain and diarrhea | ECCO

There is a considerable overlap between symptoms of IBS and IBD.

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