Recommended in Dermatology

  • Univadis
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ESMO 2017 : Adjuvant therapy with nivolumab superior to ipilimumab in surgically resected stage III and IV melanoma according to CheckMate 238 trial

The 18-months interim analysis shows a moderate benefit in terms of relapse-free survival with much fewer side effects and therapy termination.

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  • Clinical Essentials from J Am Acad Dermatol
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Plaque psoriasis: ixekizumab demonstrates long-term safety, efficacy

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  • Clinical Essentials from N Engl J Med
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Stage III/IV resected melanoma: nivolumab tops ipilimumab as adjuvant therapy

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  • Clinical Essentials from J Am Acad Dermatol
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Psoriasis: systemic biologics raise infection risk

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  • Clinical Essentials from N Engl J Med
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BRAF+ melanoma: adjuvant dabrafenib/trametinib boosts DFS

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  • Clinical Essentials from JAMA Dermatol
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Patients with psoriasis 60% more likely to die of alcohol-related causes

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  • Clinical Essentials from Br J Dermatol
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Atopic dermatitis: IEC advises against routine use of systemic corticosteroids

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  • Univadis
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ASCO 2017 - Melanoma brain mets: nivolumab+ipilimumab deliver promising phase 2 results

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  • Clinical Essentials from Am J Transplant
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Voriconazole raises SCC risk in lung transplant recipients

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Professional Essentials

  • Patients Will Be Asking

Are my microbes making me fat?

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  • US Professional News
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Physician gave office manager 39 drugs

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  • US Professional News
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Insurers targeted for opioid practices

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  • US Professional News
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Job market for residents a "feeding frenzy"

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  • US Professional News
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Whistleblowing neurosurgeon gets $17.5 million

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  • US Professional News
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Many patients interested in financing treatment: survey

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New in Dermatology

  • Clinical Essentials from JAMA Dermatol
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Pediatric psoriasis: one drug is less safe than others

A comparative analysis of systemic therapies.

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  • Clinical Essentials from N Engl J Med
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Advanced melanoma: nivolumab/ipilimumab combination boosts OS

Data from the CheckMate 067 phase 3 clinical trial.

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  • Clinical Essentials from Br J Dermatol
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Plaque psoriasis: secukinumab bests FAEs in open-label study

First comparison of secukinumab to FAEs, the currently recommended first-line treatment in Europe.

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  • Clinical Essentials from Eur J Cancer
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Early melanoma: no survival benefit for ultrasound follow-up

Appropriate follow-up strategy remains unclear.

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  • Clinical Essentials from J Am Acad Dermatol
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Psoriasis: systemic TNFi therapy increases malignancy risk

Data from the Psoriasis Longitudinal Assessment Registry.

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Skin Cancer Vitals for September 2017
  • Vitals
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Skin Cancer Vitals for September 2017

Pembrolizumab bests ipilimumab in melanoma | No SCC risk with vismodegib for BCC | Optimal adjuvant RT dose for Merkel cell carcinoma.

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  • Clinical Essentials from JAMA Neurol
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Anti-PD-1 therapy tied to a diverse array of neurologic complications

A cohort study of patients receiving pembrolizumab or nivolumab for solid-organ malignancies

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  • Clinical Essentials from Br J Dermatol
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Psoriasis: extension study confirms 3-y efficacy for secukinumab

Data from the SCULPTURE extension study shows PASI 90 rate of 64%..

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  • Clinical Essentials from BMC Cancer
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Cutaneous melanoma: prognostic factors in stage 3 disease

Three factors can help identify patients at high risk for relapse

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  • Clinical Essentials from J Eur Acad Dermatol Venereol
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Psoriasis: ixekizumab ameliorates skin-related personal relationship issues

Data from the UNCOVER-2 and UNCOVER-3 phase 3 trials.

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  • Clinical Essentials from Dermatol Ther
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Toenail fungus: topical prophylaxis reduces recurrence

Additional evidence supports use of topical antifungal products as prophylactic treatment.

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  • Clinical Essentials from Br J Dermatol
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Dupilumab boosts QoL in patients with atopic dermatitis

The study further supports the use of dupilumab in AD.

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  • Clinical Essentials from Int J Womens Health
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Women with perimenopausal vaginal atrophy may benefit from CO2 laser

CO2 laser associated with few complications in perimenopausal women.

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  • Clinical Essentials from Br J Dermatol
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Working in the sun raises risk for cutaneous SCC

Most strategies have focused on curtailing leisure exposure.

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