Recommended in Gastroenterology

  • Clinical Essentials from Am J Gastroenterol
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IBS is underdiagnosed and undertreated in the US

Up to 48 million Americans are thought to be affected by IBS.

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  • Clinical Essentials from J. Clin. Oncol
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HCC: is sorafenib more effective in HCV+ patients?

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  • Clinical Essentials from Lancet Gastroenterol Hepatol
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IBD: do psychological therapies improve outcomes?

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  • Clinical Essentials from FDA
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FDA: MRI can cause malfunction of implantable pumps

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  • Clinical Essentials from PLoS One
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Barrett's esophagus: do PPIs reduce esophageal cancer risk?

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  • Clinical Essentials from Dig Liver Dis
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HCC: CYP1A2 expression predicts recurrence in patients with HCV

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  • Clinical Essentials from Nutrients
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Drinking coffee lowers liver stiffness in HCV, HBV, and NAFLD

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  • Clinical Essentials from Br J Cancer
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Gastrointestinal cancer: post-diagnosis aspirin use boosts survival

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  • Clinical Essentials from Inflamm Bowel Dis
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Elderly IBD: comprehensive care should address physical QoL

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Professional Essentials

  • Patients Will Be Asking

Will running relieve my joint pain?

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  • Patients Will Be Asking

Can I get tested for HPV?

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  • US Professional News

US needs more black physicians: commentary

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  • US Professional News

FDA releases draft guidance on how drugmakers can share off-label information with physicians

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  • US Professional News

Online reviews of providers are here to stay

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  • US Professional News

New Medicare payment models: 359,000 clinicians are now participating

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New in Gastroenterology

  • Clinical Essentials from Biomed Pharmacother
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Antidepressants to treat cancer? SSRIs show oncolytic and chemosensitizing effects

A review of published evidence suggests that SSRIs combat more than cancer-related depression.

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  • Clinical Essentials from Aliment Pharmacol Ther
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HCV-3: prescribers quick to adopt new treatment regimens

Real-world data show rapid evolution of therapeutic strategies during 20-mo period.

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  • Clinical Essentials from Clin Res Hepatol Gastroenterol
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SOF+DCV highly effective for HCV-1 and HCV-3 in LT recipients

Meta-analysis suggests efficacy may be hampered by add-on RBV.

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  • Clinical Essentials from J Community Med Health Educ
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Survey: PCPs remain unwilling to treat HCV in the DAA era

Although the majority was aware of DAAs, few agreed that they should be offered in primary care.

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  • Clinical Essentials from Hepatol Int
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Post-LT HCV-1: LDV/SOF highly effective without RBV

Current guidelines recommend add-on ribavirin, but its value remains controversial.

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  • Clinical Essentials from J Am Coll Cardiol
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What is behind “aspirin resistance” in type 2 diabetes?

Enteric-coated aspirin is associated with a lower antiplatelet response as a result of impaired gastrointestinal absorption.

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  • Clinical Essentials from Amyotroph Lateral Scler Frontotemporal Degener
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ALS: PEG placement lowers risk of tracheostomy or death

PEG placement after physician recommendation improves tracheostomy-free survival.

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  • Clinical Essentials from Ann Hepatol
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Post-LT HCV: SOF+DCV highly effective without RBV

Small study includes patients with HIV coinfection, decompensated cirrhosis.

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  • Clinical Essentials from Aliment Pharmacol Ther
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IBD: vitamin D levels influence response to anti-TNFs

Vitamin D has been linked to disease activity and duration of anti-TNF therapy in patients with IBD.

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  • Clinical Essentials from PLoS One
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HCV-4: can first-line simeprevir-PR be shortened to 12 wk?

Small phase 3 study shows 97% clearance rate in early responders with mild-moderate fibrosis.

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  • Clinical Essentials from Gastroenterology
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Infectious enteritis quadruples risk for IBS

Results of a meta-analysis.

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  • Clinical Essentials from J Viral Hepat
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HBV and breast cancer chemotherapy: a meta-analysis of lamivudine prophylactic efficacy

LAM reduces reactivation-related treatment disruption, but RAVs may develop.

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Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors
  • The New England Journal of Medicine
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Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors

The addition of 177Lu-Dotatate to octreotide resulted in an 18% response rate and a significantly higher rate of progression-free survival.

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  • Clinical Essentials from Br J Clin Pharmacol
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Unexpected risk associations for DOACs, including with musculoskeletal complaints

Some DOACs showed stronger risk associations than others.

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