Recommended in Hospital Medicine

  • Clinical Essentials from JAMA
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Norepinephrine in short supply is linked to increased mortality from septic shock

The most common substitute when norepinephrine is not available is phenylephrine.

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  • Clinical Essentials from JAMA Pediatr
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Acute kidney injury found in two-thirds of children with DKA

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  • Clinical Essentials from Curr Opin Crit Care
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Bedside clinical assessment essential for better sepsis outcomes

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  • Clinical Essentials from J Am Coll Cardiol
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Tolvaptan doesn’t yield early dyspnea improvement in acute HF despite inducing rapid weight loss

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  • Clinical Essentials from Mayo Clin Proc
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In-hospital “stress hyperglycemia” raises type 2 diabetes risk

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  • Clinical Essentials from Amyotroph Lateral Scler Frontotemporal Degener
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Fractures: a harbinger of ALS?

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  • Clinical Essentials from Pediatrics
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Community-acquired pneumonia: large study highlights inappropriate antibiotic choices for children

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  • Clinical Essentials from Hypertension
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Continuing prestroke antihypertensives does not affect outcomes

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  • Clinical Essentials from MMWR Morb Mortal Wkly Rep
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Chinese avian influenza A(H7N9) spike: CDC update

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Professional Essentials

  • US Professional News

Most states now allowing experimental drug access

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  • US Professional News

CMS delays some bundled payments

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  • US Professional News

Time for kickback rules to reflect new payment models

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  • US Professional News

Texas physician penalized by IRS for personal loan

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  • Patients Will Be Asking

How am I supposed to squeeze in 2 h of walking a day?

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  • Patients Will Be Asking

Is it better to have kids when you're older or younger?

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New in Hospital Medicine

  • Clinical Essentials from JAMA
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Sedation strategy with dexmedetomidine does not improve mortality rates in sepsis

Sedation with dexmedetomidine offers only minor benefit.

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  • Clinical Essentials from Int J Chron Obstruct Pulmon Dis
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COPD: post-ED case management slashes readmission rates

Patients received in-home clinical assessment, medication review, and education.

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  • Clinical Essentials from BMC Neurol
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Leukoaraiosis predicts stroke-associated pneumonia

SAP is associated with poor functional outcomes, necessitating predictive markers.

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Dose-dependent mortality risk observed for Afib patients taking digoxin | ACC
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Dose-dependent mortality risk observed for Afib patients taking digoxin | ACC

Approximately 30% of patients with Afib worldwide take digoxin.

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  • Clinical Essentials from N Engl J Med
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Early goal-directed therapy not superior to routine care in sepsis

Case-by-case decision making is recommended.

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Rivaroxaban reduces VTE recurrence compared with aspirin | ACC
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Rivaroxaban reduces VTE recurrence compared with aspirin | ACC

The first direct comparison of rivaroxaban and aspirin in this population.

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  • Clinical Essentials from J Am Geriatr Soc
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Sleep problems tied to postsurgical delirium in older adults

Postoperative delirium is common but untreatable, whereas sleep-based prevention strategies are known to be effective.

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  • Clinical Essentials from Am J Emerg Med
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Emergency departments are frontline resource for combating antibiotic resistance

Avoidance of antibiotics for skin, soft tissue, and upper respiratory infections are key to reducing the antibiotic resistance burden.

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  • Clinical Essentials from Ann Emerg Med
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Pediatric asthma: ED revisits common after hospitalization

About 40% of children revisited the emergency department within 1 y.

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  • Clinical Essentials from Eur J Heart Fail
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More obesity paradox: abdominal obesity linked to better eplerenone outcomes in HFrEF

Eplerenone improves outcomes for all patients, but especially those with abdominal obesity.

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  • Clinical Essentials from J Obes
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MS and bariatric surgery: procedure appears relatively safe, beneficial

Bariatric surgery is a reasonable treatment option for morbidly obese patients with MS who are surgical candidates.

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  • Clinical Essentials from PLoS One
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Community acquired pneumonia: can ultrasound play a role in prognostic stratification?

First study demonstrating the prognostic role of TUS in pediatric patients with CAP suggests a broader application of TUS beyond diagnostic.

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  • Clinical Essentials from Cochrane Database Syst Rev
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Uncontrolled asthma: is adjunct anti-leukotriene better than increased ICS dose?

A new Cochrane review of 37 studies.

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  • Clinical Essentials from Crit Care Med
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New-onset Afib undetected in 1 in 12 ICU patients

Afib detected in 1 in 5 ICU patients overall.

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