Recommended in Hospital Medicine

  • Clinical Essentials from JAMA
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New sepsis, septic shock guidelines released

Updated recommendations highlight need for antibiotic stewardship, more dynamic intervention.

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  • Clinical Essentials from Pain
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Opioids no better than NSAIDs for chronic pain after car crash

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  • Clinical Essentials from Antimicrob Agents Chemother
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Selecting pneumonia antimicrobials: how does ceftazidime-avibactam measure up?

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  • Clinical Essentials from Lancet Respir Med
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Severe influenza: is intravenous zanamivir an option for hospitalized patients?

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  • Clinical Essentials from CMAJ
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Bacterial pneumonia: is there added diagnostic value to measuring CRP?

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  • Clinical Essentials from Pediatrics
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PICC lines needed on pneumonia discharge? Expert comment

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  • Clinical Essentials from Lancet
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Enhanced disinfection strategies recommended to reduce multidrug resistance during hospital admission

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  • Clinical Essentials from JAMA
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Sepsis: qSOFA >2 most prognostic for in-hospital mortality

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  • Clinical Essentials from PNAS
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Carbapenem-resistant enterobacteriacae more widespread than believed

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Professional Essentials

  • Patients Will Be Asking

Can I get tested for HPV?

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  • Patients Will Be Asking

Will running relieve my joint pain?

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  • US Professional News

Online reviews of providers are here to stay

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  • US Professional News

New Medicare payment models: 359,000 clinicians are now participating

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  • US Professional News

FDA releases draft guidance on how drugmakers can share off-label information with physicians

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  • US Professional News

US needs more black physicians: commentary

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New in Hospital Medicine

  • Clinical Essentials from Minerva Anestesiol
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Hysterectomy: lidocaine plus dexmedetomidine yields multiple benefits

Randomized study shows reduced post-op pain and fentanyl use, faster recovery of bowel function.

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  • Clinical Essentials from Clin Radiol
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Uterine artery embolization: oxycodone CR curbs post-op pain, morphine intake

Results of a randomized controlled trial.

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  • Clinical Essentials from N Engl J Med
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Transmission implicated for rapid expansion of extremely drug-resistant TB

Transmission, rather than inadequate TB treatment, likely responsible for rapid spread of XDR TB.

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  • Clinical Essentials from BMJ Open
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Sepsis risk is sharply higher in ALS

Patients with ALS, especially those on life support, have a much higher risk for sepsis than patients free of this disease.

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  • Clinical Essentials from Cardiovasc Toxicol
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Ozone as an HF therapy?

Small study shows some benefit of ozone therapy on some outcomes in HFrEF.

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  • Clinical Essentials from CMAJ
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Pneumonia: meta-analysis suggests adding C-reactive protein measurement

Previous meta-analyses suffered from heterogeneity, using different combinations of signs and symptoms with CRP measurement.

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  • Clinical Essentials from JAMA
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qSOFA, SIRS: limited utiliity for predicting mortality in ICU setting

Both qSOFA and SIRS criteria perform suboptimally compared with SOFA for predicting sepsis-associated in-hospital mortality.

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  • Clinical Essentials from Circ Heart Fail
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Revascularization beats medical management for survival in HFrEF patients

CABG seemed to yield better outcomes than PCI.

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  • Clinical Essentials from Eur J Prev Cardiol
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Multivessel disease predicts mortality in type 1 diabetes

In those referred for coronary angiography, number of affected coronary vessels influences mortality.

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  • Clinical Essentials from Sci Rep
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Patients with cancer pain have higher levels of anxiety, depression

More than 50% of patients with cancer fail to have adequate pain relief.

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  • Clinical Essentials from BMC Infect Dis
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Community-acquired pneumonia: results suggests optimal empiric therapy

Previous efficacy and new cost-effectiveness data support beta-lactam monotherapy.

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  • Clinical Essentials from Australas Emerg Nurs J
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Parkinson's disease: ED visits largely due to falls

Patients with PD have a high admission rate and longer stay than most older adults.

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  • Clinical Essentials from J Am Heart Assoc
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What is the role of perioperative beta-blockers in diabetes patients undergoing noncardiac surgery?

Previous findings have conflicted, and timing has not been addressed.

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  • Clinical Essentials from J Am Heart Assoc
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Aldosterone doesn't predict CV events after ACS in non-HF patients

Hormone already known to predict risk in ACS patients with advanced HF.

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