Recommended in Pharmacy

  • Clinical Essentials from J Clin Oncol
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Which NHL survivors have greatest risk for HF?

The study recommends preventive strategies in the newly diagnosed.

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  • Clinical Essentials from Pharma Res Per
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Montelukast: neuropsychiatric side effects common in adults and children

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  • Clinical Essentials from Am. J. Transplant.
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SOF-based regimens clear 96% HCV in dual LKT recipients

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  • Clinical Essentials from J Clin Oncol
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Prostate cancer: comorbidity does not raise cancer-specific mortality

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  • Clinical Essentials from J Natl Cancer Inst
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Breast cancer: extended AI therapy tied to CV events, bone fractures

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  • Clinical Essentials from J. Hepatol
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DAA-induced HCV clearance dramatically reduces HCC risk

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  • Clinical Essentials from Psychother Psychosom
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Antidepressant dose escalation may not work

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  • Clinical Essentials from Lancet
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Asthma in the real world: once-daily fluticasone plus vilanterol beats usual care

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  • Clinical Essentials from Int. J. Clin. Pract
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HCV: pharmacist-led program prevents harmful drug interactions

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Professional Essentials

  • Patients Will Be Asking

Should I be taking more "cheat days?"

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  • US Professional News
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Trauma researcher recounts his own

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  • Patients Will Be Asking

Should I throw away my child’s foam dart guns?

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  • US Professional News
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Data registries tied to MACRA bonuses

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  • US Professional News
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Physicians often too busy to sleep or eat well

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  • US Professional News
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Physician describes helping patients end lives

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New in Pharmacy

Pain and Opioid Abuse Vitals for September 2017
  • Vitals
  • 1 comment

Pain and Opioid Abuse Vitals for September 2017

TMS in migraine | Ibuprofen lozenge for sore throats | Reducing nipple pain in breastfeeding.

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  • Clinical Essentials from J Natl Cancer Inst
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Early breast cancer: no survival benefit for 5 vs 2.5 y of extended endocrine therapy

The IDEAL trial did find the reduction of second primary breast cancer with 5 y extra treatment.

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  • Clinical Essentials from Lancet Respir Med
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Earlier successful extubation if sedation halted right after surgery

Results from the Strategy of Optimized Sedation­-Ventilation (SOS­Ventilation) study.

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  • Clinical Essentials from Am J Prev Med
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Young adult women less likely to receive diabetes prevention efforts

Waiting until pregnancy to deliver lifestyle interventions may be “too little, too late.”

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  • Clinical Essentials from BJU Int
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Penile SCC: front-line dacomitinib shows promise in phase 2 trial

Dacomitinib is an irreversible, pan-epidermal growth factor receptor inhibitor.

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  • Clinical Essentials from Lancet Psychiatry
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In mania, olanzapine is less effective in mild illness

Clinicians should consider benefit-to-risk ratio with olanzapine for patients with mild mania symptoms.

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  • Clinical Essentials from J Am Board Fam Med
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Are your diabetes patients using alternative medicine?

Study finds about half are using complementary health approaches, some with possible adverse effects.

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  • Clinical Essentials from Ann Oncol
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HER2+ breast cancer: high post-NACT TILs predict poorer DFS

Some may benefit from a 2nd-line therapy, including immune checkpoint inhibitors.

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  • Clinical Essentials from J Am Coll Cardiol
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Dabigatran registry study finds high probability of long-term adherence

Half of those who discontinued, however, did not start a new OAC within 30 d.

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Skin Disease Vitals for September 2017
  • Vitals
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Skin Disease Vitals for September 2017

Dupilumab and QoL in atopic dermatitis | Long-term secukinumab efficacy in psoriasis | Cancer risk with systemic TNFi.

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  • Clinical Essentials from J Am Coll Cardiol
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Beta-blockers add little to ACEi/ARB and statins for mortality prevention post acute MI

Nonadherence to these drugs is linked to higher mortality.

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  • Clinical Essentials from Vaccine
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Pediatric pneumonia hospitalization with 10- and 13-valent pneumococcal vaccines

Novel vaccines offer reduced hospitalization risk compared with older or no vaccine.

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  • Clinical Essentials from JAMA Neurol
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Pioglitazone after stroke: benefit may be greater for high-risk patients

A secondary analysis of the IRIS trial.

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  • Clinical Essentials from JAMA
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Prolonged antibiotic prophylaxis after CD may reduce risk for SSI in obese women

Oral cephalexin and metronidazole for 48 h may reduce the risks in women with ROM.

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