Recommended in Pharmacy

  • Clinical Essentials from Hematol Oncol
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Biosimilar EPO-α: safe, effective in chronic lymphoid neoplasms

More than 7 in 10 patients responded.

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  • Clinical Essentials from Neurology
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Diabetic peripheral neuropathy: which drugs work best?

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  • Clinical Essentials from Ann Intern Med
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ACP: treat substance abuse as a chronic condition

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  • Clinical Essentials from FDA
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  • FULLTEXT

FDA approves Zejula maintenance therapy for recurrent ovarian cancer

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  • Clinical Essentials from Pediatr Blood Cancer
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Pediatric ALL: fluconazole delivers prophylaxis without increasing vincristine toxicity

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  • Clinical Essentials from Lancet Diabetes Endocrinol
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Combination heart failure drug could improve glycemic control

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  • Clinical Essentials from BMC Infect Dis
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HIV: lamivudine + dolutegravir dual therapy shows promising results

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  • Clinical Essentials from Arab J Gastroenterol
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HCV: DAAs linked to reports of herpes reactivation

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  • Clinical Essentials from Cancer
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AML: treosulfan-based conditioning improves survival outcomes, reduces toxicity

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Professional Essentials

  • Patients Will Be Asking

Is salt behind my midnight bathroom trips?

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  • Patients Will Be Asking

Patients Will Be Asking: Can I be awake for my surgery?

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  • Patients Will Be Asking

Is my nut allergy real?

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  • US Professional News

Upwardly mobile physicians need business, leadership skills

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  • US Professional News

Midwest states best for physicians, says personal finance website

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  • US Professional News

ACA's future depends on bureaucrats, insurers

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New in Pharmacy

  • Clinical Essentials from Cancer
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Imatinib remains drug of choice for unresectable KIT+ melanoma

Dasatinib shows limited activity in a phase 2 trial.

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  • Clinical Essentials from Sci Rep
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NSCLC with brain metastases: RT adds no OS benefit to icotinib

The combination does extend duration of intracranial control.

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  • Clinical Essentials from PLoS One
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TKIs for NSCLC: study highlights importance of monitoring EGFR mutations

Close monitoring may be able to detect resistance in a timely manner.

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  • Clinical Essentials from Int J Gynecol Cancer
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Vulvar cancer: surgery may not be needed with optimal RT/CRT

Study evaluates options for primary treatment of locally advanced disease.

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  • Clinical Essentials from J Pediatr Gastroenterol
  • 1 comment

HBV vaccination: 72% of children with IBD have low titers

Type of immunosuppressive therapy does not appear to influence titer.

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  • Clinical Essentials from N Engl J Med
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Multicenter RCT of levosimendan for postcardiac surgery hemodynamic support stopped

No survival effects seen vs placebo.

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Lipids and CAD Vitals for March 2017
  • Vitals
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Lipids and CAD Vitals for March 2017

Risk equation for ASCVD in FH | Limited adoption of cholesterol guideline | Inclisiran and PCSK9 and LDL | Evolucumab and cardiovascular events

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  • Clinical Essentials from FDA
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FDA approves avelumab for metastatic Merkel cell carcinoma

The PD-L1 inhibitor is approved for use in patients aged 12 y and older.

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Asthma and COPD Vitals for March 2017
  • Vitals
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Asthma and COPD Vitals for March 2017

LAMA+LABA for COPD | No link between inhaled corticosteroids, pneumonia in pediatric asthma | Aclidinium/formoterol safe, effective for COPD.

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  • Clinical Essentials from Aliment Pharmacol Ther
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Eluxadoline for IBS-D: early response predicts long-term effect

A post-hoc analysis of two phase 3 studies.

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  • Clinical Essentials from BMC Neurol
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Interferon-β-1a for MS: predictors of discontinuation identified

Data from a cohort study of over 5900 patients.

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  • Clinical Essentials from Breast Cancer
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Advanced HR+ breast cancer: adding targeted agents to fulvestrant boosts PFS

Results of a meta-analysis.

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  • Clinical Essentials from Cancer
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High-risk prostate cancer: docetaxel, ADT add benefit to adjuvant radiation

Data from the RTOG 0621 study.

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  • Clinical Essentials from J Am Assoc Nurse Pract
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HPV: how common is vaccination among lesbian and bisexual women?

Study contradicts prior data suggesting lower uptake vs heterosexual women.

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