Recommended in Pulmonology

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ASCO 2017 - Advanced SCLC: promising results with nivolumab±ipilimumab

Results were so encouraging, 247 patients were added to the original 159.

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ASCO 2017 - NSCLC: phase 3 study suggests prolonged survival benefit with atezolizumab

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ASCO 2017 - Extensive-stage SCLC after chemotherapy: favorable OS with pembrolizumab in phase 2 trial

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ASCO 2017 - ALK+ NSCLC: ceritinib + nivolumab shows activity in phase 1 trial

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ASCO 2017 - Phase 2 data support first immunotherapy for mesothelioma

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ASCO 2017 - Treatment-naïve advanced ALK+ NSCLC: alectinib tops crizotinib for PFS

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ASCO 2017 - EGFR+ advanced NSCLC: 5.5-mo PFS advantage for dacomitinib vs standard therapy

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ASCO 2017 - High-intensity ctDNA assay promising in metastatic breast, lung, and prostate cancers

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  • Clinical Essentials from Cochrane Database Syst Rev
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  • FULLTEXT

Cochrane review: umeclidinium in COPD

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Professional Essentials

  • US Professional News

Discussion can convince vaccine doubters

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FTC, AG shut down ND merger

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High billing codes require scrutiny

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Provider groups oppose Senate health bill

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  • Patients Will Be Asking

Is Zika still a threat?

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  • US Professional News

MACRA reporting eased in proposal

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New in Pulmonology

  • Clinical Essentials from Eur Respir J
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COPD and smoking: which patients are more likely to quit?

Study identifies predictors of long-term smoking cessation.

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  • Clinical Essentials from Parkinsonism Relat Disord
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Parkinsonism: gastrostomy fails to prevent aspiration pneumonia

A study of patients with Parkinson’s disease or atypical parkinsonism.

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  • Clinical Essentials from Crit Care
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Varicella-associated pneumonia: do adjunctive steroids help or hurt?

Data from the largest study on VZV-CAP.

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Only 16% of patients with asthma completely adherent | EAACI
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Only 16% of patients with asthma completely adherent | EAACI

Study highlights need for stronger belief that benefits outweigh potential harm.

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  • Clinical Essentials from JAMA Oncol
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NSCLC: delayed adjuvant chemotherapy shows benefit

Adjuvant chemotherapy is effective even when started 7-18 wk post-resection.

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  • Clinical Essentials from Invest New Drugs
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ES-SCLC: amrubicin is a viable treatment option for certain patients

Phase 2 data show benefit in chemotherapy-naive elderly, poor-risk patients.

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PCV13 vaccine immune response tops PPSV23 in CLL | EHA
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PCV13 vaccine immune response tops PPSV23 in CLL | EHA

Immune response superior in 10 out of 12 serotypes after one month.

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Grass pollen SLIT lowers risk of asthma onset and progression | EAACI
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Grass pollen SLIT lowers risk of asthma onset and progression | EAACI

Asthma progression improved by 24.6% during treatment and 15.2% after cessation.

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  • Clinical Essentials from Cancer Epidemiol Biomarkers Prev
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HIV: increased cancer screening may be warranted

People with HIV are living full lives on ART, opening the door for new causes of death.

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  • Clinical Essentials from Clin Microbiol Infect
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Pneumonia in nursing homes: simple severity prediction tool

Study provides a simple tool to individualize the treatment of NHAP.

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  • Clinical Essentials from Lung Cancer
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SCLC: no benefit for toxicity-adjusted cisplatin-etoposide dosing

Results of the phase 3 STAD-1 trial.

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  • Clinical Essentials from Chest
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Chest Expert Cough Panel: recommendations on chronic cough in children

The most common etiologies vary according to age and location.

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Significant clinical benefit shown in SCIT for dog/cat allergen | EAACI
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Significant clinical benefit shown in SCIT for dog/cat allergen | EAACI

The greatest improvement seen with pulmonary symptoms followed by nasal and ocular symptoms.

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  • Clinical Essentials from BMC Infect Dis
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CAP: should atypical pathogens be covered in empiric treatment?

Findings support major guidelines from Europe and the Infectious Diseases Society of America.

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