Recommended in Urology

Primary Care Cancer Vitals for January 2017
  • Vitals
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Primary Care Cancer Vitals for January 2017

Avoiding unnecessary prostate biopsies | How much exercise to prescribe? | Kaposi’s sarcoma and UV radiation | No PSA testing linked to high-risk disease.

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  • Clinical Essentials from JAMA Oncol
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Prostate cancer: PSA nadir >0.5 ng/mL after RT/ADT identifies high-risk for death

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  • Clinical Essentials from Prostate Cancer Prostatic Dis
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Prostate cancer: does the new ISUP grouping system improve accuracy of risk prediction?

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  • Clinical Essentials from BJU Int
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Non-muscle invasive bladder cancer: a summary of current guidelines

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  • Clinical Essentials from Biomed Pharmacother
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Antidepressants to treat cancer? SSRIs show oncolytic and chemosensitizing effects

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  • Clinical Essentials from Urol Oncol
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Prostate cancer: high-tech facilities have lower racial disparities in care

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  • Clinical Essentials from Lancet Oncol
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Urothelial cancer: pembrolizumab shows durable response in advanced disease

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  • Clinical Essentials from BMC Urol
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Localized prostate cancer: does HIFU deliver on expectations of better QoL?

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  • Clinical Essentials from Acta Neurol Belg
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Bladder dysfunction in MS: prevalence, correlates over time characterized

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Professional Essentials

  • US Professional News

New Medicare payment models: 359,000 clinicians are now participating

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  • US Professional News

Online reviews of providers are here to stay

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  • US Professional News

FDA releases draft guidance on how drugmakers can share off-label information with physicians

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  • US Professional News

US needs more black physicians: commentary

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  • US Professional News

Survey finds a third of uninsured or sick patients feel disrespected by providers

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  • US Professional News

Physicians could find themselves shut out of hospitals' bundling approach

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New in Urology

  • Clinical Essentials from Prostate Cancer Prostatic Dis
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Prostate cancer: metformin effects consistent across ethnicities

The jury is still out on metformin and prostate cancer, but effects do not differ between Chinese vs non-Chinese groups

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  • Clinical Essentials from J. Antimicrob. Chemother
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Significant antimicrobial-resistant E. coli, Klebsiella UTI seen in long-term care facility residents

Clinicians caring for residents of LTCF should select/use antibiotics judiciously, after surveillance efforts to guide management.

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  • Clinical Essentials from J Clin Oncol
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Locally advanced urothelial carcinoma: adjuvant chemotherapy boots survival after RNU

First large-scale study of patients with upper tract urothelial carcinoma undergoing upfront radical nephroureterectomy.

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  • Clinical Essentials from Acta Oncol
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MCRPC: low NLR linked to improved survival with docetaxel

Neutrophil-to-lymphocyte ratio ≤3 was associated with a mean benefit in OS of almost 15 mo.

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Surrogate end points for all-cause mortality in prostate cancer patients
  • JAMA Oncology
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Surrogate end points for all-cause mortality in prostate cancer patients

Comparison of surrogate end points for death in patients with localized and unfavorable-risk prostate cancer.

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  • Clinical Essentials from BJU Int
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Prostate cancer: salvage HIFU after EBRT failure yields 72% OS at 7 y

Treatment should be initiated early in men with locally recurrent prostate cancer after EBRT failure.

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  • Clinical Essentials from Diabetes Metab Res Rev
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Diabetes raises postoperative cognitive dysfunction risk

Evidence extends relatively well-established role of hyperglycemia in age-related cognitive impairment.

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  • Clinical Essentials from BJU Int
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Prostate cancer: PHI density testing could avoid 38% of unnecessary biopsies

Of 5 methods evaluated, PHI density demonstrated the highest discriminative ability for clinically-significant cancer.

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High risk HLA incompatible kidney transplant in sensitized patients has no survival benefit
  • The Lancet
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High risk HLA incompatible kidney transplant in sensitized patients has no survival benefit

Transplant waiting time in sensitized patients is much longer

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  • Clinical Essentials from Radiat Oncol
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Prostate cancer: does radiation therapy raise the risk for second cancers?

Although RT did not raise the overall risk, the incidence of some specific cancers was higher.

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  • Clinical Essentials from Cancer Epidemiol
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Prostate cancer: worse inhospital outcomes in US blacks vs whites

Factors appear to extend beyond access to hospital care.

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Heart Failure Vitals: January 2017
  • Vitals
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Heart Failure Vitals: January 2017

Cancer-related cardiac dysfunction | Limitations of HF risk models | HF and urinary incontinence

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  • Clinical Essentials from Prostate Cancer Prostatic Dis
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Prostate cancer: no/incomplete PSA testing linked to high-risk disease in older men

Johns Hopkins study suggests abandoning PSA testing in older men could lead to more deaths.

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  • Clinical Essentials from Clin Cancer Res
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Advanced RCC: dalantercept shows promise in phase 2 trial

Results support a randomized phase 2 trial using the 0.9 mg/kg dose in combination with axitinib.

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