ASCO 2022 – Hope SHINEs for elderly patients with mantle cell lymphoma

Elena Riboldi — Agenzia Zoe | Conference Report | 07 June 2022

The SHINE study shows a 50% improvement in progression free survival for newly diagnosed patients treated with a combination of targeted and chemoimmunotherapy

Takeaway

In elderly patients with newly diagnosed mantle cell lymphoma (MCL), the addition of ibrutinib to standard-of-care chemoimmunotherapy (bendamustine-rituximab, BR) and rituximab maintenance significantly improved progression free survival (PFS).

Why this matters

MCL is often diagnosed in people aged 65 years or over.
Outcomes of MCL are greatly unsatisfactory...

ASCO 2022 – Hope SHINEs for elderly patients with mantle cell lymphoma

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