ASCO 2023 – Combination Therapy Triples Survival Rate in Richter Syndrome

Masssimo Sandal | Conference Report | 09 June 2023

A three-drug combination regimen could induce durable remission in patients with Richter syndrome with diffuse large B-cell lymphoma.

In a recent phase II clinical trial, MOLTO, completed in February 2023, a combination therapy of atezolizumab, obinutuzumab and venetoclax demonstrated a significant improvement in response and survival rates for patients with Richter syndrome, specifically those with diffuse large B-cell lymphoma ( RS -DLBCL).

A median survival of 31.6 months ...

ASCO 2023 – Combination Therapy Triples Survival Rate in Richter Syndrome

September Challenge

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What is the primary risk factor for type 2 diabetes worldwide?

What are the risk factors for osteosarcopenia?

Is regular statin intake linked to a reduced rate of hepatocellular carcinoma?

Asymptomatic carotid stenosis: what are the recommended therapeutic options for carotid stenting?

Vertebral artery disease: what are the recommended imaging strategies?

What is the effect of metformin therapy on bone mineral density?

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What are the physiological reactions of chromium in the body?

How do you manage acute coronary syndrome in patients receiving anticancer therapy?

What is the association between drugs approved for weight management and cardiovascular mortality?

What do you know about breast milk and its nutritional quantity?

Is there a lifetime increased risk for breast cancer in patients with meningioma?

Does vitamin D level influence colorectal cancer outcomes?

What are the effects of the COVID-19 pandemic and the incidence of diabetes in children?

Fluoroquinolones: what are the latest updates from the European Medicines Agency?

What are the special considerations for the management of atopic eczema?

Is maternal obsessive-compulsive disorder linked to adverse neonatal outcomes?

Does early live attenuated measles/mumps/rubella vaccine lower infection-related hospitalisation in infants?

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