Asymptomatic pyuria: a risk factor for adverse pregnancy outcomes
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- Asymptomatic pyuria during pregnancy is associated with adverse birth outcomes.
Why this matters
- Asymptomatic bacteriuria affects 4% to 40% of pregnant women.
- Routine urine culture in pregnant women during the first trimester is recommended.
- It has been postulated that the mechanism of urinary tract infections and preterm birth are related to the production phospholipase A2 by microorganisms that activates prostaglandins.
- Urine analysis is less expensive than urine culture and can quickly detect pyuria.
- Pyuria was associated with increased risk for preterm delivery (<36 wk, OR, 2.231; P=.009).
- Pyuria was associated with increased risk for preterm premature rupture of membranes (PPROM, OR, 4.269; P=.003).
- Pyuria was associated with low birth weight (OR, 1.758; P=.035).
- Pyuria was associated with low Apg...36>