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Avelumab plus talazoparib for advanced solid tumours

Heather Mason   |   24 November 2022

Adding the poly(ADP-ribose) polymerase (PARP) inhibitor talazoparib to the immune checkpoint inhibitor avelumab did not result in the extension of the clinical activity of either agent used as a monotherapy for most patients. However, a subset of patients benefited from the combination treatment, highlighting the need for optimised patient selection....

          

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