Can HRT reduce the risk for depression in perimenopause?

Access to the full content of this site is available only to registered healthcare professionals. Register to read more

Takeaway

  • Hormone replacement therapy (HRT) reduces risk for depressive symptoms when used early in transition, especially in women reporting more baseline stress events.

Why this matters

  • Sensitivity to estrogen fluctuations during perimenopause has been implicated in risk for depres...