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Data from healthcare facilities in Washington, DC, demonstrate carbapenem-resistant Enterobacteriaceae (CRE) endemicity within and across healthcare facilities in the District of Columbia.
More widespread than previously believed, with great potential for community and hospital colonization, CRE infections represent a significant clinical and public health concern requiring the establishment of baseline regional rates and ongoing surveillance.
Why this matters
CRE infections have limited or no treatment options, and invasive CRE infections are associated with mortality rates ≤50%.
Data demonstrating the likelihood of CRE transmission within clustered regional healthcare facilities highlight the need for multidisciplinary clinical awareness of transmission risks, coordinated diagnosis, and prevention.
Overall, 53 samples tested positive for CRE, with a prevalence of 5.2% (95% CI, 3.9%-6.8%).