Community-acquired pneumonia ups risk of future heart failure, especially in young adults
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Substantially increased short- and long-term risk for incident heart failure after in- or outpatient pneumonia across all adult age-groups.
Why this matters
Postdischarge cardiovascular prevention might be warranted, including awareness that subsequent dyspnea might be new-onset heart failure.
Prospective, population-based study.
Adults with community acquired pneumonia admitted to any of 6 hospitals or 7 emergency departments in Edmonton, Canada.
Up to 5 frequency matched control patients per patient.
Primary outcome was subsequent heart failure-related hospitalization.
4988 patients and 23,060 control patients.
Median follow-up was 9.9 y.
Patients had higher rate of incident heart failure than control patients (P<.001), including within 90 d of index event (P=.015), at 1 y (P<.001), and combined endpoint of incident heart failure or all cause mortality (P<.001).
10-y heart failure risk after pneumonia was approximately 12%.