Community-onset pneumonia: what role for pneumococcal urinary antigen testing?

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Takeaway

  • Pneumocococcal urinary antigen testing (UAT) is inexpensive and noninvasive and can lead to significant narrowing of empiric antibiotic therapy.

Why this matters

  • Targeted antibiotic therapy towards Streptococcus pneumonia is reasonable even if pneumocococcal UAT is the only positive microbiologic test.

Study design

  • “Real world,” multihospital observational study.
  • Secondary analysis, electronic medical data.
  • Adult emergency department patients admitted with radiographic evidence of community-onset pneumonia.
  • Usual care cultures, viral, and UAT at clinician discretion.
  • Review of those with positive pneumocococcal UAT to determine effect on antibiotic treatment.
  • Funding: Intermountain Research and Medical Foundation, Salt Lake City, UT.

Key results

  • 283...