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Clinical Summary

COVID-19: post-vax thrombotic reactions are linked to anti-PF4 antibody response

Scully M & al.. N Engl J Med, 10 June 2021
Liz Scherer   |   16 June 2021

Takeaway

  • A rare, pathologic platelet-activating anti-PF4 antibody reaction may develop in some people following the first dose of the ChAdOx1 nCoV-19 vaccine.
  • High-dose adjunctive intravenous Ig  may offer some benefit .

Why this matters

  • Rapid identification is crucial.
  • Authors say platelet transfusions should...

          

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