Diabetes/Endocrinology

General Medicine

HIV/Infectious Diseases

Pulmonary Medicine

CROI 2022 — COVID-19 pneumonia: enpatoran delivers on safety but fails to meet efficacy endpoint

Pavankumar Kamat | Conference Report | 16 February 2022

The drug did not significantly reduce the time to recovery in hospitalized patients.

Takeaway

Enpatoran failed to reduce time to recovery in patients hospitalized with acute COVID-19 pneumonia, but it was safe and well-tolerated.

Why this matters

Enpatoran is an investigational highly selective inhibitor of TLR7 and TLR8, which may potentially prevent a hyperinflammatory state and cytokine storm in patients with COVID-19 pneumonia....

General Medicine

HIV/Infectious Diseases

HPV and Cervical Cancer

Obesity and Weight Management

Pain Management

Pulmonary Medicine

Sleep Disorders

Wound Management

5 PTS expert

Nasopharynx cancer: which therapy offers the highest survival rate?

5 PTS expert

What are the electrocardiogram findings in pulmonary hypertension?

5 PTS expert

What is the extent of the increased risk of progression of inflammatory bowel disease in iron deficiency anaemia?

5 PTS expert

Deep surgical site infection: what is the difference between single vs dual antibiotic load?

5 PTS expert

What is the primary risk factor for type 2 diabetes worldwide?

5 PTS expert

What are the risk factors for osteosarcopenia?

5 PTS expert

Is regular statin intake linked to a reduced rate of hepatocellular carcinoma?

5 PTS expert

Asymptomatic carotid stenosis: what are the recommended therapeutic options for carotid stenting?

5 PTS expert

Vertebral artery disease: what are the recommended imaging strategies?

5 PTS expert

What is the effect of metformin therapy on bone mineral density?

5 PTS expert

What are the risk factors associated with interstitial lung disease in patients with rheumatoid arthritis?

5 PTS expert

Is there an increased risk for ovarian cancer in postmenopausal women with polycystic ovary syndrome?

5 PTS expert

What are the physiological reactions of chromium in the body?

5 PTS expert

How do you manage acute coronary syndrome in patients receiving anticancer therapy?

5 PTS expert

What is the association between drugs approved for weight management and cardiovascular mortality?

5 PTS expert

What do you know about breast milk and its nutritional quantity?

5 PTS expert

Is there a lifetime increased risk for breast cancer in patients with meningioma?

5 PTS expert

Does vitamin D level influence colorectal cancer outcomes?

5 PTS expert

What are the effects of the COVID-19 pandemic and the incidence of diabetes in children?

5 PTS expert

Fluoroquinolones: what are the latest updates from the European Medicines Agency?

5 PTS expert

What are the special considerations for the management of atopic eczema?

5 PTS expert

Is maternal obsessive-compulsive disorder linked to adverse neonatal outcomes?

5 PTS expert

Does early live attenuated measles/mumps/rubella vaccine lower infection-related hospitalisation in infants?

5 PTS expert

What is the effect of bariatric surgery on colorectal cancer risk in patients with obesity?

5 PTS expert

What are the effects of anticoagulation therapy on atrial fibrillation patients with prior intracranial haemorrhage?

Quiz challenge Emerging diseases: COVID-19

Closed 10 Questions Available Ends on 1 October 2020

ESMO 2020 topic challenge

Closed 5 Questions Available Ends on 21 April 2021

Women's health challenge

Closed 10 Questions Available Ends on 12 May 2021

Antibiotics - Consequence of MDR carriage

Closed 6 Questions Available Ends on 12 May 2021

Neurological disorders challenge

Closed 10 Questions Available Ends on 12 June 2021

Rheumatology challenge

Closed 10 Questions Available Ends on 12 July 2021

Lyme Disease

Closed 11 Questions Available Ends on 12 July 2021

Mental health challenge

Closed 10 Questions Available Ends on 12 August 2021

Topic challenge - Children conditions

Closed 7 Questions Available Ends on 12 September 2021

Lyme Disease

Closed 11 Questions Available Ends on 12 September 2021