Dementia Vitals for February 2017

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We screened more than 919 studies on Dementia this month. These are the most important.

Symptom of kidney disease may also be risk factor for dementia

Source: J Am Geriatr Soc

  • A meta-analysis including 32 studies and 240,000 patients found that albuminuria was associated with a 35% increased risk for cognitive impairment and dementia, particularly vascular dementia (OR, 1.96) and clinical Alzheimer's disease (OR, 1.37).
  • Clinicians may want to test for albuminuria as a part of assessing a patient's risk for dementia.


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Some antidepressants may cut dementia risk

Source: Int J Clin Pharmacol Ther

  • A retrospective analysis of 90,000 depressed patients showed that those taking tricyclic and tetracyclic antidepressants had a reduced risk pf developing dementia.
  • Selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors showed no significant association with dementia risk.


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Dementia: donazepil+choline alphoscerate helps manage symptoms

Source: J Alzheimers Dis

  • Behavioral and psychological symptoms of dementia (BPSD) are common and distressing problems for both patients and caregivers.
  • In a study of 113 patients with Alzheimer's disease, donepezil taken together with choline alphoscerate helped manage BPSD. 


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Previous Vitals on Dementia: January '17December '16

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