DMTs for MS: what attributes are most important to patients?

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  • Patients with multiple sclerosis (MS) indicated that risk for side effects was the most important factor influencing their preference among disease-modifying therapies (DMTs).

Why this matters

  • Many DMTs are now available for MS, but the factors influencing patients’ preferences are not well explored.

Key results

  • The DMT attribute assigned greatest relative importance was risk for side effects (32.9%), followed by route of administration (26.1%), frequency of administration (22.7%), prevention of disease progression (10.0%), and prevention of relapse (8.3%).
  • This pattern was similar whether patients had lower or higher Expanded Disability Status Scale scores.
  • Patients who had received their diagnosis less than a year ago had the greatest importance assigned to risk for side effects (39.0%)
  • Relative im...