Does sunlight raise the risk for Kaposi's sarcoma in HIV-infected men?
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This study found that risk for Kaposi's sarcoma (KS) was increased among HIV-infected men with a history of nonmelanoma skin cancer (NMSC) and those living in locations with high ambient exposure to ultraviolet radiation (UVR) at time of HIV diagnosis.
Why this matters
The relationship between UVR and risk for KS in HIV-infected patients is unknown.
Among 17,597 HIV-infected veterans, there were 422 newly diagnosed KS cases.
Among individuals with prior NMSC, there was a statistically significant increased risk for KS (HR=8.64).
In the total cohort, KS risk was higher for quartile 4 vs 1 (HR=1.49; Ptrend=.02) and among Caucasians (HR=1.75; Ptrend=.009), but not among African Amer...