Early antibiotic use doubles risk for childhood asthma

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  • Exposure to antibiotics in the first 3 y of life was associated with increased risk of developing childhood asthma. 
  • No association between early life exposure to antibiotics and risk for exacerbation.

Why this matters

  • Increased use of antibiotics in early childhood has been reported, with the highest rate of antibiotic use (18.7%) occurring in children aged 1 mo to 18 y treated for bacterial lower respiratory tract infection. 
  • Previous studies have reported conflicting findings regarding early life antibiotic exposure and risk for childhood asthma. 
  • Based on the present findings, more judicious use of antibiotics in young children should be considered.

Study design

  • Study utilized data from 4 childhood cohorts comprising 9758 participants.
  • Funding: Health Infor...