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Conference Report

EASD 2022 — Preconception metformin in men and birth defects in offspring: is there a link?

Drishti Agarwal   |   23 September 2022

Takeaway

  • Paternal metformin treatment for diabetes approximately 3 months before conception is associated with an increased risk for major birth defects in the offspring, especially male genital birth defects.

Medications for diabetes, such as metformin, exert glucose-independent effects on the male reproductive system; however, their association with birth defects in...

          

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