EOC: high serum IL-37 levels linked to poor prognosis

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Takeaway
  • High levels of interleukin 37 (IL-37) are predictive of poor outcomes in epithelial ovarian cancer (EOC).
Why this matters
  • IL-37 may have value as a clinically potential indicator for EOC progression and a prognostic marker for survival.
Study design
  • Serum IL-37 levels were evaluated in 76 patients with EOC and 76 healthy control patients at a single center; for patients with EOC, the association of IL-37 levels with clinical factors and prognosis was analyzed.
  • Funding: None disclosed.
Key results
  • IL-37 levels from patients with EOC were 187.3±75.57 pg/mL; this was 2-fold higher compared with those of healthy control patients (84.89±28.92 pg/mL; P<.001).
  • Serum levels of IL-37 were significantly ...