ESMO 2022 – A "new" cell therapy for metastatic melanoma

Daniela Ovadia — Agenzia Zoe | Conference Report | 12 September 2022

Twenty years after the pivotal study proposing TIL therapy, a randomised phase 3 trial demonstrates its efficacy in patients who failed anti-PD-1 treatment

by Elena Riboldi (Agenzia Zoe)

Takeaway

Compared to ipilimumab, Tumour Infiltrating Lymphocytes (TIL) therapy reduced by 50% the chance of progression of the disease or dying from the disease in patients with metastatic melanoma.

Why this matters

Treatment options for patients with metastatic melanoma failing immune checkpoint inhibitors are...

ESMO 2022 – A "new" cell therapy for metastatic melanoma

September Challenge

Nasopharynx cancer: which therapy offers the highest survival rate?

What are the electrocardiogram findings in pulmonary hypertension?

What is the extent of the increased risk of progression of inflammatory bowel disease in iron deficiency anaemia?

Deep surgical site infection: what is the difference between single vs dual antibiotic load?

What is the primary risk factor for type 2 diabetes worldwide?

What are the risk factors for osteosarcopenia?

Is regular statin intake linked to a reduced rate of hepatocellular carcinoma?

Asymptomatic carotid stenosis: what are the recommended therapeutic options for carotid stenting?

Vertebral artery disease: what are the recommended imaging strategies?

What is the effect of metformin therapy on bone mineral density?

What are the risk factors associated with interstitial lung disease in patients with rheumatoid arthritis?

Is there an increased risk for ovarian cancer in postmenopausal women with polycystic ovary syndrome?

What are the physiological reactions of chromium in the body?

How do you manage acute coronary syndrome in patients receiving anticancer therapy?

What is the association between drugs approved for weight management and cardiovascular mortality?

What do you know about breast milk and its nutritional quantity?

Is there a lifetime increased risk for breast cancer in patients with meningioma?

Does vitamin D level influence colorectal cancer outcomes?

What are the effects of the COVID-19 pandemic and the incidence of diabetes in children?

Fluoroquinolones: what are the latest updates from the European Medicines Agency?

What are the special considerations for the management of atopic eczema?

Is maternal obsessive-compulsive disorder linked to adverse neonatal outcomes?

Does early live attenuated measles/mumps/rubella vaccine lower infection-related hospitalisation in infants?

What is the effect of bariatric surgery on colorectal cancer risk in patients with obesity?

What are the effects of anticoagulation therapy on atrial fibrillation patients with prior intracranial haemorrhage?

Topic Challenges

Quiz challenge Emerging diseases: COVID-19

ESMO 2020 topic challenge

Women's health challenge

Antibiotics - Consequence of MDR carriage

Neurological disorders challenge

Rheumatology challenge

Lyme Disease

Mental health challenge

Topic challenge - Children conditions

Lyme Disease