The European Alliance of Associations for Rheumatology (EULAR) has published a series of 11 points to consider for the management of difficult-to-treat rheumatoid arthritis (D2T RA).

D2T RA must meet the following three criteria:

• Treated per EULAR recommendations but failure of ≥2 biological and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) after...