Expression of matrix metalloproteinase-9 is associated with progression of oral cancer and decreased survival

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  • Expression of matrix metalloproteinase-9 (MMP-9) was positively correlated with advanced tumor stage and decreased overall survival in a meta-analysis study.

Study design
  • A total of 419 oral cancer patients from 9 studies were subjected to meta-analysis. The methodological quality of these studies was assessed for consistency in reviewing and reporting.

Key results
  • Patients positive for MMP-9 expression had significantly decreased ...