HCV: LDV/SOF highly effective as rescue therapy

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Takeaway

  • Ledipasvir/sofosbuvir (LDV/SOF)±ribavirin (RBV) achieves high HCV clearance rates in SOF-experienced, NS5A inhibitor-naïve patients, including those with cirrhosis or HIV coinfection.

Why this matters

  • There are limited data on rescue regimens after failure of SOF+simeprev...