- Higher prescription opioid dose is associated with worse patient-reported pain outcomes and more health care utilization.
Why this matters
- Previous research has examined pain-related variables on the basis of prescription opioid dose, but data from studies involving patient-reported outcomes have been limited.
- Ohio State University investigators examined the relationships between prescription opioid dose and self-reported pain intensity, function, quality of life, and mental health.
- Participants with musculoskeletal pain diagnoses who were receiving stable doses of long-term opioid therapy were recruited from two large integrated health systems.
- The researchers assigned participants into one of three groups on the basis of current prescription opioid dose in daily morphine equivalents.
- They were low dose (5-20 mg MED), moderate dose ...