History of cardiac surgery may not affect outcome of TAVI in patients with AS

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  • Meta-analysis suggests that transcatheter aortic valve implantation (TAVI) in patients with previous cardiac surgery can be performed with results similar to those of patients with no history of cardiac surgery.

Study design

  • Meta-analysis of studies from PubMed, EMBASE, and Cochrane that met the following criteria: clinical outcomes in TAVI patients, with and without previous cardiac surgery (prospective or retrospective cohort study); well-defined study population of patients with severe aortic stenosis (AS) who were inoperable or at high risk for surgical aortic valve replacement; comparison of clinical outcomes in patients with and without previous cardiac surgery; outcomes of short-term (in-hospital or 30-d) all-cause mortality; 1-y all-cause mortality, stroke or transient ischemic attack, acute myocardial infarction (MI), major bleeding events, major vascular complications, and need for permanent pacemaker placement.

Key results

  • 23 studies met criteria and included 4441 patients with previous...