How common are ischemic and bleeding events 1 y after stenting?

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Takeaway

  • Ischemic events were more common than bleeding events in patients surviving 1 y after coronary stenting via percutaneous coronary intervention (PCI), but both were associated with significantly higher mortality.

Why this matters

  • Little was known about the prognosis for late ischemic and bleeding events after PCI.

Study design

  • Secondary analysis of Dual Antiplatelet Therapy Study.
  • 11,648 patients underwent PCI, received thienopyridine + aspirin for 12 mo, then randomized to continue thienopyridine or placebo for 18 mo.
  • Funding: Harvard Clinical Research Institute, National Institutes of Health, and others.

Key results

  • At 21 mo, overall ischemic event rate 4.1% (59.2% were in placebo group, 40.8% in treatment group); 10.9% died.
  • Patients with ischemic events wer...