How does stroke affect traumatic brain injury survivors?
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In a national database study, 2.5% of patients with severe traumatic brain injury (TBI) experienced concurrent acute ischemic stroke (AIS), which was associated with worse functional and cognitive outcomes.
Why this matters
There is limited clinical evidence on AIS in TBI.
2.5% of patients experienced concurrent AIS.
Compression of basal cisterns or midline shift (OR, 1.589; P=.005), damage to subcortical white matter tracts (OR, 1.853; P<.001), and the presence of atrial flutter (OR, 3.560; P=.037) were independently associated with AIS in multivariate analysis.
AIS was associated with reduced Functional Independence Measure Total score (P<.001) and increased Disability Rating Scale total score (P<.001).
6488 patients with TBI from the Traumatic Brain Injury Model Systems National Database were analyzed for AIS incidence...