HPV-positive OPSCC: E6 expression predicts metastasis and death

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Takeaway

  • High expression of the E6 gene is associated with distant metastasis and poor survival of patients with human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC).

Study design

  • An initial cohort of 39 patients with HPV-positive OPSCC and a validation coh...