Takeaway

• A combination of liposomal irinotecan and fluorouracil plus leucovorin outperformed fluorouracil plus leucovorin alone in advanced biliary tract cancer that had progressed after gemcitabine plus cisplatin.

Why this matters

• The authors suggest that liposomal irinotecan combined with fluorouracil and leucovorin could be a standard-of-care second-line therapy.

Study design

• Open-label,...