Longer duration of dual antiplatelet therapy after stent placement Improves outcomes in peripheral arterial disease | ESC

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Takeaway

  • In this study published online by JAMA Cardiology and simultaneously presented at ESC, held in August in Rome, longer duration of dual antiplatelet therapy (DAPT) after stent placement was shown to improve outcomes in peripheral arterial disease (PAD). 

Key results

  • Prolonged DAPT duration of 24 months after PCI reduced the risk of death, heart attack, or stroke compared with short DAPT of six months or less.
  • In patients undergoing PCI, concomitant PAD was associated with a two-fold increased risk of ischemic events, whereas the risk of bleeding was unaffected.
  • The improved efficacy of prolonged DAPT in patients with PAD was not offset by an increased risk of actionable bleeding episodes. 

Study design

  • Investigators at Bern University Hospital, Bern, Switzerla...