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Lung cancer: opioid analgesia may reduce efficacy of immune checkpoint inhibitors

Miriam Davis, PhD   |   Clinical Summary   |   15 December 2022
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Background

  • The anticancer efficacy of immune checkpoint inhibitors (ICIs) may be diminished by the loss of diversity in gut microbiota because the microbiota has antitumour effects.
  • Opioid analgesia (OA) given for cancer pain influences the diversity and composition of gut microbiota.
  • Does OA given during ICI therapy for lung cancer...

          

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