Lupus: RBC distribution width correlated with fatigue in young patients | EULAR
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While standard disease activity markers did not correlate with the burden of fatigue in young patients with systemic lupus erythematosus (SLE), there was a correlation between increased red blood cell distribution width (RDW) and increased fatigue. This is the first time such a correlation has been reported.
Why this matters
The findings suggest that iron deficiency may play a significant role in the onset of fatigue, which is a common and disabling symptom in SLE.
The authors say that plans are underway for a trial of therapeutic iron infusion for SLE-related fatigue.
Thirty-seven adolescent and young adult patients with SLE completed the Functional Assessment of Chronic Fatigue Illness Therapy (FACIT) Fatigue Scale.
Standard disease activity measures were also recorded, including erythrocyte sedimentation ...