We screened 794 studies on Neurodegenerative and Neuromuscular Disorder this month. These are the most important.
Minocycline and MS risk: antibiotic reduces conversion from clinically isolated syndrome
Source: N Engl J Med
- Minocycline appears to reduce the risk for conversion of clinically isolated syndrome to multiple sclerosis (MS) in the short term.
- Minocycline has shown some benefit in patients with established MS and is generally safe.
Huntington's disease: plasma levels of NfL are linked to prognosis
Source: Lancet Neurol
- Among HTT mutation carriers, plasma neurofilament light protein (NfL) correlated with changes in cognitive function, motor function, and brain volume.
- There is no clinical blood test for estimating Huntington's disease onset and prognosis.
PD: extended-release amantadine useful for levodopa-induced dyskinesia
Source: JAMA Neurol