Nonparoxysmal Afib: is catheter ablation better than antiarrhythmics?
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- Taking on the question of which is better for nonparoxysmal Afib, this meta-analysis gives the win to catheter ablation for preventing recurrences, decreasing hospitalizations at 1 y.
Why this matters
- Ablation has already shown a clear benefit in paroxysmal Afib, but only 3 trials were available for assessment of its benefits in nonparoxysmal Afib.
- Current recommendations are radiofrequency ablation in symptomatic nonparoxysmal Afib intractable to medication or for Afib continuous for 1 y; the current results support recommendations.
- All trials used radiofrequency catheter ablation.
- More ablation patients were arrhythmia free at 1 y vs antiarrhythmic group (69% vs 35%; risk ratio, 1.84).
- There were less card...