Diabetes/Endocrinology

General Medicine

HIV/Infectious Diseases

Pulmonary Medicine

Obstructive sleep apnea: noradrenergic+antimuscarinic therapy is safe and effective

Miriam Davis, PhD | Clinical Summary | 15 June 2022

Meta-analysis of 9 RCTs finds improved apnea-hypopnea index, among other outcomes.

Takeaway

A meta-analysis finds that pharmacotherapy specifically with combined noradrenergic plus antimuscarinic agents is safe and efficacious for lessening the severity of obstructive sleep apnea (OSA).

Why this matters

No pharmacotherapy currently enjoys routine use for OSA.

Study design

Systematic review and meta-analysis of 9 randomized controlled trials (RCTs) involving 154...

Obesity and Weight Management

Pain Management

Pulmonary Medicine

Sleep Disorders

Wound Management

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