One-third of patients have Afib before TAVI

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  • One-third of patients undergoing transcatheter aortic valve implantation (TAVI) have preexisting atrial fibrillation (Afib).
  • Patients with preexisting Afib or new Afib after TAVI have a significantly higher 1 y mortality rate than those without Afib, especially patients discharged on single antiplatelet therapy.

Study design

  • A retrospective, multicenter study.
  • 708 patients underwent TAVI for severe, symptomatic aortic stenosis.
  • Patients divided into 3 group: sinus rhythm (SR, n=423, 59.7%), preexisting Afib (n=219, 30.9%), and new onset Afib (NOAF) (n=66, 9.3%).
  • Funding: Source of funding not disclosed.

Key results

  • Patients with preexisting Afib and those with NOAF had a higher rate of 1 y all-cause mortality compared to those in SR (14.6% vs 6.5% for preexisting Afib and 16.3% vs 6.5% for NOAF; P=.007).
  • Similar inhospital and 30 d mortality rates, 30 d and 1 y stroke/transient ischemic attack rate, and bleeding among all groups.
  • Patients with either preexisting or new Afib discharged on single a...