Opioid dependence: positive long-term outcomes with ED buprenorphine continued in primary care

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  • For opioid dependence, emergency department (ED)-initiated buprenorphine (Suboxone) with continuation in primary care (the intervention) was associated with increased engagement in addiction treatment and lower illicit opioid use at 2 mo post-discharge, but not at 6 and 12 mo.

Why this matters

  • Nonmedical use of opioids has reached epidemic proportions and interventions are needed to retain patients in care.

Study design

  • This was an extension study of 88% of the cohort that had been randomized in an earlier controlled trial (n=329).
  • Patients in the ED had been randomly assigned to the intervention, referral, or brief intervention.
  • Main outcome measures were self-reported engagement in formal addiction treatment, days of illicit opioid use.
  • Fu...