OPSCC: 3 factors for survival after salvage resection

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  • Lymph node metastasis, clinical stage, and gastrostomy tube dependence are associated with reduced survival of patients with oropharyngeal squamous cell carcinoma (OPSCC) after salvage surgical resection.

Key results

  • The recurrence rate after salvage surgery was higher in human papilloma virus (HPV)-negative patients (P=.05).
  • 2 y and 5 y OS rates were 49% and 26%, respectively.
  • 5 y OS was not associated with HPV status (P=.05) or smoking status (P=.09).
  • 5 y OS was significantly associated with cervical lymph node metastasis (P=.008), advanced tumor stage (P=.04), and gastrostomy tube dependence (P=.007).

Study design

  • 69 patients with OPSCC who underwent...