OPSCC: prolonged diagnosis-to-treatment interval associated with poor survival outcomes

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Takeaway

  • A diagnosis-to-treatment interval (DTI) 30 d is associated with increased mortality risk for patients with oropharyngeal squamous cell carcinoma (OPSCC).

Study design

  • 6606 patients with stage III-IV OPSCC receiving chemoradiation were analyzed for associations between DTI and outcomes.

Key results

  • Patients with prolonged DTI had significantly decreased overall survival (HR=1.12 [95% CI 1.04-1.20], P=.005).
  • Prolonged DTI was significantly associated with intens...