Oral cancer: national database indicates improved prognosis over time

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  • Analysis of the US National Cancer Database suggests that three-year overall survival of oral cavity squamous cell carcinoma (OCSCC) patients has improved.

Key results

  • Disease diagnosis between 2004-2006 was significantly associated with improved survival for both early- and late-stage disease compared with 1998-2003 (p<.001 for both).
  • Rates of adjuvant chemoradiation treatment increased from 8.3% to 36.4% for late-stage disease patients.
  • Treatment in a high-volume center and neck dissection were significantly associated with improved survival for all stages (p=.002 and p=.001, respectively).

Study design

  • 13,655 OCSCC pati...