Oropharyngeal cancer: high myoferlin expression predicts poor outcomes
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- High expression of the membrane protein myoferlin is associated with poor recurrence and survival outcomes of oropharyngeal squamous cell carcinoma (OPSCC) patients.
- Nuclear myoferlin expression was significantly associated with recurrence (p<.001), perineural invasion (p=.008), extracapsular spread (p-.009), higher T-stage (p=.0015), and distant metastasis (p<.001).
- Nuclear myoferlin expression was associated with reduced overall survival (p<.001).
- 211 OPSCC patients were analyzed for myoferlin expression and associati...